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Gene silencing: Maintaining methylation patterns

Current BiologyPublished 1 August 1999Open access
Steven E. Jacobsen
Citations23
SJR quartileQ1
SJR score2.71
SNIP1.83
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TL;DR

Recent studies of an Arabidopsis gene family have shown that inverted repeats can be potent silencers of other identical sequences in the genome, causing them to become stably methylated at cytosine residues.

Abstract

Recent studies of an Arabidopsis gene family have shown that inverted repeats can be potent silencers of other identical sequences in the genome, causing them to become stably methylated at cytosine residues. From mutations affecting this process we are beginning to understand how methylation patterns are maintained.

Keywords

Agricultural and Biological Sciences