Top Research Papers on Stress

It is found although the concept of stress is developed from Selye's “general adaptation syndrome”, it has now expanded and evolved significantly and is now defined as a state of homeostasis being challenged, including both system stress and local stress.

Grand challenges in understanding stress-induced RNA condensation are outlined, centering on the unique and substantial barriers in the molecular study of cellular structures, such as stress granules, for which no biological function has been firmly established.

This review will briefly discuss the adverse effects of key abiotic stresses such as cold, heat, drought, and salinity, and the importance of biotechnological tools in the development of stress-tolerance cultivars.

It is explained how altering second-level valuation systems-shifting the valuation of stress from "is bad for me" to "can be good for me"-fundamentally changes the overarching goal of stress regulation from reducing stress to optimizing stress responses to achieve valued goals.

Part One: Theoretical Perspectives in Occupational Research Psychological Stress in the Workplace Work Stress Conceived and Researched Transactionally Measuring Occupational Stress: The Job Stress Survey. Part Two: Sources and Consequences of Occupational Stress: Model Testing Coping with Stressful Life Events: An Empirical Analysis A Field Study of Some Antecedents and Consequences of Felt Job Stress. Part Three: The Impact of Persistence on Stressor-Strain and Strain-Intentions to Leave Relationships: A Field Examination. Part Four: An Examination of Burnout Individual, Organisational, and S...

How and to what extent Pro is involved in relieving oxidative stress to regulate plant survival under extreme environments is discussed and an overview on adopting advanced genome-editing technologies, such as CRISPR, for editing appropriate genes of Pro metabolism aiming to develop stress-resistant crop plants is presented.

This review assesses how UPR signaling mediators can influence antioxidant responses and how oxidative stress can disrupt the function of redox-sensitive organelles including the mitochondria and endoplasmic reticulum.

A conceptual model of acute and chronic stress pathophysiology as a continuum in chronic disease development is discussed and a brief overview on the organization and physiology of the human stress system and its (re)activity is offered.

Changes in parent stress longitudinally from before (retrospective) to two timepoints during COVID-19 are described, suggesting the need for enhanced mental health resources and supports.

Comparison of tolerant and susceptible potato cultivars indicates that single and multiple abiotic stress tolerance in potato is associated with a maintenance of CO2 assimilation and protection of PSII by a reduction of light harvesting capacity and suggests that stress tolerant cultivars suppress cell death and maintain growth and development via fine tuning of hormone signaling, and primary and secondary metabolism.

Recent studies suggesting that reciprocal regulation between stress-response and growth-control pathways occurs at multiple levels will be critical for resetting the balance between stress resistance and growth in order to engineer stress-resistant and high-yielding crops.

This review outlines the contributions of autophagy, oxidative stress, and ER stress in neurodegenerative conditions along with a particular focus on the crosstalk among these pathways and provides a comprehensive discussion on the potential of nanomaterials to target this crosStalk and suggest this potential as a promising opportunity in neuroprotection.

The physiological, biochemical, and molecular mechanisms underlying abiotics stress-induced anthocyanins in plants and their role in abiotic stress tolerance are discussed and practical guidance for plant biologists who are engineering stress-tolerant crops using Anthocyanin biosynthesis or regulatory genes is provided.

A BDNF stress–sensitivity hypothesis is proposed, which posits that disruption of endogenous BDNF activity by common factors potentiates sensitivity to stress and, by extension, vulnerability to stress-inducible illnesses.

The mechanisms underlying susceptibility and resilience to acute and chronic stress are discussed, providing insight into the potential underpinnings of the sex bias of neuropsychiatric disorders.

The current study presented the first meta-analytic review on the associations between the Big Five personality traits and stress measured under different conceptualizations (stressor exposure, psychological and physiological stress responses) using a total of 1,575 effect sizes drawn from 298 samples. Overall, neuroticism was found to be positively related to stress, whereas extraversion, agreeableness, conscientiousness, and openness were negatively linked to stress. When stress assessed under different conceptualizations was tested, only neuroticism, agreeableness, and conscientiousness wer...

The promise of redox proteomics and systems biology is focused on to help fully understand the relationship between ROS and hypertension and their potential for designing and evaluating novel antihypertensive therapies.

Plants are continuously exposed to different environmental stress conditions that have a huge impact on agriculture worldwide, consequently leading to massive economic losses. These adverse conditions alter the metabolism of reactive oxygen and nitrogen species (ROS and RNS). High concentrations of these reactive species—that exceed the capacity of antioxidant defense enzymes—disturb redox homeostasis, which can trigger damage to such macromolecules as membrane lipids, proteins, and nucleic acids, ultimately resulting in nitro-oxidative stress and plant cell death. Significant progress has bee...

During progression and metastasis, tumor cells adapt to oxidative stress by increasing NADPH in various ways, including activation of AMPK, the PPP, and reductive glutamine and folate metabolism.

A comprehensive strategy that integrates anatomical, biomechanical and biological risk factors has the potential to improve the understanding of bone stress injuries and aid in their prevention and management.