Pluripotent Stem Cell Function of the Mouse Marrow "Lymphocyte"
SciencePublished 15 May 1964
Gustavo Cudkowicz, Michael V. L. Bennett, G M Shearer
Citations87
SJR quartileQ1
SJR score10.42
SNIP6.62
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Abstract
Bone marrow from normal and polycythemic mice was filtered through glasswool columns to remove cells other than "lymphocytes." For a given number of nucleated cells, filtered marrow was more efficient than the original marrow in repopulating the spleen of an isogenic recipient previously exposed to lethal irradiation. The proliferative capacity of both the filtered and unfiltered marrow suspensions appeared to be a constant function of the number of small and medium "lymphocytes" present and not of any other cell type.
Keywords
Medicine
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