Interventions for treating depression after stroke
Cochrane Database of Systematic ReviewsPublished 8 October 2008Open access
Maree L. Hackett, Craig S. Anderson, Allan House, Jun Xia
Citations350
SJR quartileQ1
SJR score1.62
SNIP2.04
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TL;DR
A small but significant effect of pharmacotherapy (not psychotherapy) on treating depression and reducing depressive symptoms was found, as was a significant increase in adverse events, which is required before recommendations can be made about the routine use of such treatments.
Abstract
A small but significant effect of pharmacotherapy (not psychotherapy) on treating depression and reducing depressive symptoms was found, as was a significant increase in adverse events. More research is required before recommendations can be made about the routine use of such treatments.
Keywords
MedicineNeuroscience
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80 Citations2004Nicoletta Aimonino Ricauda, Mario Bo +6 more
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76 Citations2006Sharon K. Ostwald, Joan Wasserman +1 more
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63 Citations2004M Hackett, CS Anderson +1 more
A review of Randomised and quasi-randomised controlled trials comparing different types of pharmaceutical agents with placebo, or various forms of psychotherapy with standard care in patients with recent, clinically diagnosed, acute stroke found no evidence to support the routine use of pharmacotherapeutic or psychotherapy for depression after stroke.
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55 Citations1990Lucy Yu, Thomas J. Rohner +4 more
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46 Citations2001Juhani Sivenius, Taneli Sarasoja +4 more
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Treatment with moclobemide for 6 months did not enhance the regression of aphasia following an acute stroke, and multivariate regression analysis including treatment group, activities of daily living, aetiology of stroke, ANELT, and Reinvang’s coefficient at baseline confirmed these results.
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