The road less traveled
The Journal of Cell BiologyPublished 29 July 2002Open access
Craig R. Roy, Lewis G. Tilney
Citations284
SJR quartileQ1
SJR score3.36
SNIP1.52
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TL;DR
This review will focus on recent studies that have identified bacterial proteins and host processes that play a concerted role in transporting Legionella to the ER.
Abstract
Phagosomes containing the bacterial pathogen Legionella pneumophila are transported to the ER after macrophage internalization. To modulate phagosome transport, Legionella use a specialized secretion system that injects bacterial proteins into eukaryotic cells. This review will focus on recent studies that have identified bacterial proteins and host processes that play a concerted role in transporting Legionella to the ER.
Keywords
Biochemistry, Genetics and Molecular Biology
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