Affect, cognition, the immune system and health
Progress in brain researchPublished 1 January 2000
Margaret E. Kemeny, Tara L. Gruenewald
Citations26
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TL;DR
This chapter discusses the linkages between the mind and the immune system, focusing on the newer evidence that cognitive states have immunological correlates.
Abstract
A growing body of evidence in the field of psychoneuroimmunology documents the linkages between the mind, brain, and immune system. The central and autonomic nervous systems can engage in bidirectional communication with immunologic cells in the blood, tissue, and immune organs. It remains unclear whether immunologic changes observed in conjunction with stressors are responsible for observed relationships between stress and immunologically mediated or resisted diseases. This chapter discusses the linkages between the mind and the immune system, focusing on the newer evidence that cognitive states have immunological correlates. It begins by reviewing research linking exposure to stressful life experiences to immune system functioning, primarily in humans. It then reviews the research on affect, the regulation of affect, and the immune system including studies of affective disorders, such as major depression, mood states (such as depressed and anxious mood), and emotions such as sadness. It then turns to the research indicating that specific cognitive states, including beliefs, have immunological and health correlates.
Keywords
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AIDS Education and PreventionEffects of AIDS-Related Bereavement on HIV Progression Among New York City Gay Men
104 Citations1995Margaret E. Kemeny, Laura Dean
The data suggest that bereavement may impact biological systems relevant to HIV progression and that distinguishing specific responses to loss may improve the understanding of these relationships.
Physiology & BehaviorSocial confrontation and tumor metastasis in rats: Defeat and β-adrenergic mechanisms
100 Citations1996Volker Stefanski, Shamgar Ben‐Eliyahu
The findings suggest that the nature of intruder-resident interaction, rather than being subdominant or exposure to an unfamiliar environment, has a marked influence on the intruder's susceptibility to metastatic development.
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