Mapping of human chromosome 5 microsatellite DNA polymorphisms
GenomicsPublished 1 November 1991
James L. Weber, Mihael H. Polymeropoulos, Paula E. May, Anne E. Kwitek, Hong Xiao, John D. McPherson
Citations74
SJR quartileQ2
SJR score0.85
SNIP0.77
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TL;DR
Thirteen moderately to highly informative microsatellite DNA polymorphisms based on (dC-dA)n.(dG-dT)n repeats were mapped to segments of human chromosome 5 using both linkage analysis and a panel of somatic cell hybrids which contained rearranged chromosomes.
Abstract
Thirteen moderately to highly informative microsatellite DNA polymorphisms based on (dC-dA)n.(dG-dT)n repeats were mapped to segments of human chromosome 5 using both linkage analysis and a panel of somatic cell hybrids which contained rearranged chromosomes. The markers were distributed throughout most of the length of the chromosome from the regions p15.3-p15.1 to q33.3-qter. Maps of the sites of meiotic recombination within the reference families proved particularly useful for the purpose of integrating new polymorphisms into the existing linkage map.
Keywords
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