SMART: a web-based tool for the study of genetically mobile domains
Nucleic Acids ResearchPublished 1 January 2000Open access
J. Schultz
Citations1,442
SJR quartileQ1
SJR score7.78
SNIP4.71
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TL;DR
SMART (a Simple Modular Architecture Research Tool) allows the identification and annotation of genetically mobile domains and the analysis of domain architectures.
Abstract
SMART (a Simple Modular Architecture Research Tool) allows the identification and annotation of genetically mobile domains and the analysis of domain architectures (http://SMART.embl-heidelberg.de ). More than 400 domain families found in signalling, extra-cellular and chromatin-associated proteins are detectable. These domains are extensively annotated with respect to phyletic distributions, functional class, tertiary structures and functionally important residues. Each domain found in a non-redundant protein database as well as search parameters and taxonomic information are stored in a relational database system. User interfaces to this database allow searches for proteins containing specific combinations of domains in defined taxa.
Keywords
Biochemistry, Genetics and Molecular Biology
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