Neurobiological Mechanisms of the Placebo Effect
Journal of NeurosciencePublished 9 November 2005Open access
Fabrizio Benedetti, Helen S. Mayberg, Tor D. Wager, Christian S. Stohler, Jon-Kar Zubieta
Citations759
SJR quartileQ1
SJR score1.96
SNIP1.30
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It is necessary to eliminate the specific action of a therapy and to simulate a context that is similar in all respects to that of a real treatment to study this psychosocial context.
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The British Journal of PsychiatryPlacebo response in depression: Bane of research, boon to therapy
128 Citations2001Gavin Andrews
Placebo controlled trials are appropriate when there is no existing treatment for a disorder, otherwise comparison trials are indicated.
AnesthesiologyDose-dependent Regional Cerebral Blood Flow Changes during Remifentanil Infusion in Humans
124 Citations2001Klaus J. Wagner, Frode Willoch +5 more
Insight into the mechanisms of opioid analgesia within the pain-processing neural network may lead to a better understanding of antinociception and opioid treatment.
PainPlacebo analgesia and the heart
119 Citations2003Antonella Pollo, Sergio Vighetti +2 more
It is shown that placebo analgesia is accompanied by a reduced &bgr;‐adrenergic activity of the heart, a effect that was reversed by naloxone, which indicates that placebo morphine is accompaniedby a complex cascade of events which affect the cardiovascular system.
American Journal of PsychiatryValidity of Clinical Trials of Antidepressants
118 Citations2000Frederic M. Quitkin, Judith G. Rabkin +3 more
The authors note that some researchers have suggested that the interpretation of psychotherapy trials can be complicated by "allegiance effects," and investigators of all orientations must guard against potential bias.
Archives of General PsychiatryUse of Pattern Analysis to Predict Differential Relapse of Remitted Patients With Major Depression During 1 Year of Treatment With Fluoxetine or Placebo
115 Citations1998Jonathan W. Stewart, Frederic M. Quitkin +8 more
These findings confirm that pattern analysis validly differentiates true drug from nonspecific initial responses and extend its use to the continuation and maintenance phases of treatment for depression.
Brain Behavior and ImmunityConditioned immunomodulation: Research needs and directions
114 Citations2003Robert Ader
It is now clear that immune function is influenced by autonomic nervous systems activity and by the release of neuroendocrine substances from the pituitary, and immunologic reactivity can be influenced by stressful life experiences or by Pavlovian conditioning.
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