The APACHE III Prognostic System
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Abstract
To the Editor: We are writing concerning the article by Knaus et al,1Knaus WA Wagner DP Draper EA Zimmerman JE Bergner M Bastos PG et al.The APACHE III prognostic system: risk prediction of hospital mortality for critically ill hospitalized adults.Chest. 1991; 100: 1619-1636Abstract Full Text Full Text PDF PubMed Scopus (3141) Google Scholar which appeared in the December 1991 issue of Chest. In that article the authors compare the overall correct classification rates, based on 2×2 classification tables with 0.50 cutpoint, for our Mortality Probability Model (MPM)2Lemeshow S Teres D Avrunin JS Gage RW Refining intensive care unit outcome prediction by using changing probabilities of mortality.Crit Care Med. 1988; 16: 470-477Crossref PubMed Scopus (143) Google Scholar and the APACHE III system. The MPM system consists of distinct models at admission to the intensive care unit (ICU), at 24 h, and at 48 h. The authors correctly chose the 24-h MPM, rather than the admission MPM, as the basis for their comparison with APACHE III, but their figure of 79.1 percent total correct classification for the MPM is incorrect. That number appears in a table in our article in which values are given for patients in the ICU for 48 h or more. The accurate overall correct classification rate for the 24-h MPM, given in the text of the article, is 84.9 percent, much closer to the APACHE III rate of 88.1 percent than the value presented. This error in research was probably inadvertent, but is nevertheless misleading. The APACHE III Prognostic SystemCHESTVol. 102Issue 6PreviewTo the Editor: Full-Text PDF
