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External validation of prognostic models for critically ill patients required substantial sample sizes

Journal of Clinical EpidemiologyPublished 6 February 2007
Niels Peek, Daniëlle G. T. Arts, Robert-Jan Bosman, Peter H. J. van der Voort, Nicolette F. de Keizer
Citations92
SJR quartileQ1
SJR score3.15
SNIP2.66

TL;DR

Substantial sample sizes are required for performance assessment and model comparison in external validation of prognostic models for outcome at intensive care units (ICUs) andCalibration statistics and significance tests should not be used in these settings.

Abstract

Substantial sample sizes are required for performance assessment and model comparison in external validation. Calibration statistics and significance tests should not be used in these settings. Instead, a simple customization method to repair lack-of-fit problems is recommended.

Keywords

MathematicsMedicine