Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor
SciencePublished 9 March 1984
Hans Marquardt, Michael W. Hunkapiller, Leroy Hood, George J. Todaro
Citations671
SJR quartileQ1
SJR score10.42
SNIP6.62
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TL;DR
The complete amino acid sequence of rat transforming growth factor type 1 has been determined and this growth factor, obtained from retrovirus-transformed fibroblasts, is structurally and functionally related to mouse epidermal growth factor and human urogastrone.
Abstract
The complete amino acid sequence of rat transforming growth factor type 1 has been determined. This growth factor, obtained from retrovirus-transformed fibroblasts, is structurally and functionally related to mouse epidermal growth factor and human urogastrone. Production of this polypeptide by various neoplastic cells might contribute to the continued expression of the transformed phenotype.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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