Patient support and education for promoting adherence to highly active antiretroviral therapy for HIV/AIDS
Cochrane Database of Systematic ReviewsPublished 18 July 2006Open access
Sergio Rueda, Laura Park‐Wyllie, Ahmed M. Bayoumi, Anne‐Marie Tynan, Tony Antoniou, Sean B. Rourke
Citations300
SJR quartileQ1
SJR score1.62
SNIP2.04
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TL;DR
A pharmacist-led program of educational and supportive counseling is the only available intervention which has been shown in a controlled study to improve adherence to HAART, with less evidence that viral load is subsequently reduced.
Abstract
We found evidence to support the effectiveness of patient support and education interventions intended to improve adherence to antiretroviral therapy. Interventions targeting practical medication management skills, those interventions administered to individuals vs groups, and those interventions delivered over 12 weeks or more were associated with improved adherence outcomes. There is a need for standardization and increased methodological rigour in the conduct of adherence trials.
Keywords
Immunology and MicrobiologyMedicine
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68 Citations2003Peter J. Dunbar, David Madigan +7 more
JAIDS Journal of Acquired Immune Deficiency SyndromesStability of Adherence to Highly Active Antiretroviral Therapy Over Time Among Clients Enrolled in the Treatment Adherence Demonstration Project
67 Citations2003James M. Tesoriero, Tyler French +4 more
Investigation of the stability of adherence over time among HIV-infected individuals attending adherence support programs in New York State found that, for some, it was the transition from a desirable to an undesirable state that increased the likelihood of nonadherence, rather than the presence of these characteristics over time.
AIDS CareThe impact of improved self-efficacy on HIV viral load and distress in culturally diverse women living with AIDS: the SMART/EST women's project
67 Citations2004Gail Ironson, Stephen M. Weiss +9 more
Changes in self-efficacy over time would be related to changes in disease progression markers (CD4, viral load) in a sample of women with AIDS and increases in cognitive behavioral skills self- efficacy were significantly related to decreases in viral load.
AIDS Patient Care and STDsBrief Motivational Interviewing to Improve Adherence to Antiretroviral Therapy: Development and Qualitative Pilot Assessment of an Intervention
67 Citations2004Monica S. Adamian, Carol E. Golin +2 more
An intervention to improve ART adherence is developed and pilot-tested, based on brief motivational interviewing (MI), which has successfully improved selected health behaviors but has not been tested for ART adherence.
PubMedAdherence to antiretroviral regimens in HIV-infected patients: results of a survey among physicians and patients.
65 Citations1998J E Gallant, D S Block
International Journal of STD & AIDSRandomized trial of an adherence programme for clients with HIV
65 Citations2003Christopher K. Fairley, R Levy +8 more
This adherence package included an education programme, individualized planning of regimens, and the opportunity for a patient to choose from a number of adherence aids and reminder devices that improved self reported adherence to antiretroviral therapy.
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