Sialic Acid in Normal and Dry Eye Tear Fluid
Advances in experimental medicine and biologyPublished 1 January 2002
Yo Nakamura, Norihiko Yokoi, Hideki Tokushige, Shigeru Kinoshita
Citations12
SJR quartileQ3
SJR score0.37
SNIP0.20
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TL;DR
The periodic acid-Schiff (PAS) method has been used to measure mucin in the stomach and small intestine, because it is the main constituent of the mucus layer and contributes to tear film stability and viscosity.
Abstract
Mucin is a particularly important component in the pathogenesis of dry eye, because it is the main constituent of the mucus layer and contributes to tear film stability and viscosity.1 Although several methods can detect mucin in tear film, mucin measurement is difficult because of its high molecular weight. Based on the fact that mucin is composed of many glycoproteins,2 the periodic acid-Schiff (PAS) method has been used to measure it in the stomach and small intestine.
Keywords
MedicineBiochemistry, Genetics and Molecular BiologyPharmacology, Toxicology and Pharmaceutics
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