Enzymic synthesis of deoxyribonucleic acid
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TL;DR
The product of replication of T7 DNA by Escherichia coli polymerase showed a branched structure with as many as 12 ends, which appears early in the course of replication and persists in the product isolated free from template and enzyme.
Abstract
Native T7 DNA is seen in the electron microscope as a continuous fiber about 11 μ, long, without branches. The product of replication of T7 DNA (and also phage λ DNA) by Escherichia coli polymerase showed, in a large number of the molecules, a branched structure with as many as 12 ends. Branching appears early in the course of replication and persists in the product isolated free from template and enzyme.