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Circadian Cycling of the Mouse Liver Transcriptome, as Revealed by cDNA Microarray, Is Driven by the Suprachiasmatic Nucleus

Current BiologyPublished 1 April 2002Open access
Ruth A. Akhtar, Akhilesh B. Reddy, Elizabeth S. Maywood, Jonathan D. Clayton, Verdun M. King, Andrew G. Smith
Citations777
SJR quartileQ1
SJR score2.71
SNIP1.83
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TL;DR

Temporally complex, circadian programming of the transcriptome in a peripheral organ is imposed across a wide range of core cellular functions and is dependent on an interaction between intrinsic, tissue-specific factors and extrinsic regulation by the SCN central pacemaker.

Abstract

Temporally complex, circadian programming of the transcriptome in a peripheral organ is imposed across a wide range of core cellular functions and is dependent on an interaction between intrinsic, tissue-specific factors and extrinsic regulation by the SCN central pacemaker.

Keywords

MedicineNeuroscience