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Albendazole for lymphatic filariasis

Cochrane Database of Systematic ReviewsPublished 7 October 2005Open access
David G. Addiss, Carrol Gamble, Paul Garner, Hellen Gelband, Henry OD Ejere, Julia Critchley
Citations57
SJR quartileQ1
SJR score1.62
SNIP2.04
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TL;DR

There is insufficient evidence to confirm or refute that albendazole co-administered with DEC or ivermectin is more effective than DEC oriver mectin alone in clearing microfilariae or killing adult worms.

Abstract

There is insufficient evidence to confirm or refute that albendazole co-administered with DEC or ivermectin is more effective than DEC or ivermectin alone in clearing microfilariae or killing adult worms. Albendazole combined with ivermectin appears to have a small effect on microfilaraemia, but this was not consistently demonstrated. The effect of albendazole against adult and larval filarial parasites, alone and in combination with other antifilarial drugs, deserves further rigorous research.

Keywords

Immunology and MicrobiologyMedicineEnvironmental Science