A fragment of the simian virus 40 early genome can induce tumors in nude mice
Journal of VirologyPublished 1 March 1985Open access
S Pan, Lauren Sompayrac, Barbara B. Knowles, Kathleen J. Danna
Citations14
SJR quartileQ1
SJR score1.28
SNIP0.90
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TL;DR
Cell lines transformed by simian virus 40 mutant F8dl (deleted from 0.168 to 0.424 map units, corresponding to the carboxy-terminal 62% of the wild-type simianirus 40 large tumor antigen) are tumorigenic in nude mice.
Abstract
Cell lines transformed by simian virus 40 mutant F8dl (deleted from 0.168 to 0.424 map units, corresponding to the carboxy-terminal 62% of the wild-type simian virus 40 large tumor antigen) are tumorigenic in nude mice. Four of five C3H10T1/2 cell lines transformed by F8dl were tumorigenic in nude mice, whereas two of two wild-type transformants were tumorigenic.
Keywords
MedicineEnvironmental Science
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