Integrated Family, General Practice and Mental Health Care in the Management of Schizophrenia
Journal of the Royal Society of MedicinePublished 1 April 1990Open access
Ian R. H. Falloon, William Shanahan, Marc Laporta, Haroutyon Krekorian
Citations23
SJR quartileQ1
SJR score1.71
SNIP1.79
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PsychologyMedicine
The British Journal of PsychiatryInfluence of Family Life on the Course of Schizophrenic Disorders: A Replication
1,776 Citations1972George W. Brown, J. L. T. Birley +1 more
It was argued that in a socially intrusive environment acting upon a patient whose thought disorder was in any case liable to become manifest whenever circumstances became too complicated, a patient would tend to attempt to protect himself by social withdrawal; but this process might easily go too far, leading to complete social isolation and inability to care for himself.
The British Journal of PsychiatryThe Influence of Family and Social Factors on the Course of Psychiatric Illness
1,680 Citations1976Christine Vaughn, Julian Leff
Important additive effects between various social influences and pharmacological treatments have been revealed which make it possible to predict relapse patterns in schizophrenia with considerable precision.
Archives of General PsychiatryFamily Psychoeducation, Social Skills Training, and Maintenance Chemotherapy in the Aftercare Treatment of Schizophrenia
917 Citations1986Gerard E. Hogarty
Two disorder-relevant treatments were developed: a patient-centered behavioral treatment and a psychoeducational family treatment among schizophrenic patients receiving maintenance neuroleptic treatment.
The British Journal of PsychiatryA Controlled Trial of Social Intervention in the Families of Schizophrenic Patients
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The results provide evidence for the causal role of relatives' expressed emotion (EE) in schizophrenic relapse, as well as for the therapeutic effectiveness of social intervention combined with drug treatment.
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586 Citations1985Ian R. H. Falloon
The relative efficacy of the family approach did not appear to be due to prognostic factors, rater bias, stressful life events, or the effectiveness of pharmacotherapy, and Definitive tests of these findings with respect to efficacy require further well-designed studies.
The British Journal of PsychiatryThe Community Management of Schizophrenia
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Relapse rates over nine months after discharge were significantly lower for patients in the two Behavioural Intervention, compared with Education Only and Routine Treatment groups, which give partial support for the causal role of EE in relapse.
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A trial of social intervention in families of schizophrenic patients in high social contact with high-expressed emotion (EE) relatives significantly reduced the relapse rate for patients who remained on antipsychotic medication throughout the two years.
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Clinical and social outcome were, in general, closely correlated and an overall rating of social functioning at 5 years showed no more than mild impairment for 47% of men and 74% of women, although individual items were more impaired.
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The large body of research demonstrating the effectiveness of antipsychotic drugs in the treatment of acute schizophrenia is selectively reviewed and recommendations are made concerning areas of psychopharmacologic research that require further development.
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The relapse and readmission rates of schizophrenic patients who participated in a controlled trial of a nine-month behavioural family intervention trial based on the EE status of their relatives are presented at two years.
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Patients exposed to social skills training evidenced significantly greater acquisition, generalization, and durability of social skills; their social adjustment in the community was rated as better by significant others; and they experienced fewer relapses and rehospitalizations.
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Evidence from a controlled, comparative trial indicates that oral pimozide is clinically at least as effective as depot injections of fluphenazine decanoate in the continuation therapy of a group of schizophrenic patients discharged from hospital.
The British Journal of PsychiatryThe Interaction of Life Events and Relatives’ Expressed Emotion in Schizophrenia and Depressive Neurosis
168 Citations1980Julian Leff, Christine Vaughn
There was no difference between schizophrenic and depressed patients in the rate of events in the three month period before onset or in the proportion of undesirable events, however, the two groups exhibited significantly different patterns of interaction between life events and relatives’ EE.
Schizophrenia BulletinEarly Intervention, Time-limited, Targeted Pharmacotherapy of Schizophrenia
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Preliminary experience suggests that control of schizophrenic symptomatology comparable to that obtained with maintenance drugs can be achieved with a marked reduction in medication use when the targeted strategy is applied in the context of a broad-based program of psychosocial intervention based on a comprehensive medical model.
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During the six-month posttreatment period patients who had received social skills training either continued to improve or maintained their gains on most measures, while the patients receiving day hospital treatment alone either maintained gains or lost them.
Psychiatric ServicesFamily Educational Intervention in the Treatment of Schizophrenia
95 Citations1983Christine W. McGill, Ian R. H. Falloon +2 more
It is suggested that patients and their families in family treatment programs can acquire and retain information about schizophrenia more readily than patients and families involved in individual treatment and enable them to become more effective participants in aftercare and helps surmount the problems associated with posthospital adjustment.
Archives of General PsychiatryWho Should Receive Clozapine?
91 Citations1988S.R. Marder
Soon after clinical studies of clozapine were initiated it was apparent that the drug was at least as effective as available neuroleptics and resulted in negligible extrapyramidal side effects, and it was hoped that the widespread availability of the drug would represent a major innovation in the treatment of schizophrenia.
Schizophrenia BulletinDeveloping and Maintaining Adherence to Long-term Drug-taking Regimens
65 Citations1984I. R.H. Fallon
Some of the aspects that commonly contribute to deficient compliance in clinical practice are described and suggestions for resolving these problems are offered.
New Directions for Mental Health ServicesLowering expressed emotion in relatives of schizophrenics
61 Citations1981Ruth Berkowitz, Liz Kuipers +2 more
A psychosocial program for the relatives of schizophrenic patients, in addition to regular medication, has contributed to keeping higher-risk patients well and in the community.
International review of neurobiologyThymoleptic and Neuroleptic Drug Plasma Levels in Psychiatry: Current Status
38 Citations1976Thomas B. Cooper, George M. Simpson +1 more
Lithium is the ideal drug to demonstrate the value of blood level determination in clinical psychiatry, such as it is easily measured in plasma or other body fluids and has no metabolites.
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10 Citations1984Nina R. Schooler, Joanne B. Severe
The purpose of this paper is to examine several issues that are relevant to treatment of chronic schizophrenic patients with drugs.
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3 Citations1989Ian R. H. Falloon, Victor Hole +3 more
Evidence of the benefits of continuing optimal drug therapy with psychological treatments that focus on the management of environmental stress factors is demonstrated, the strength of which makes it difficult to justify the current lack of provision of such services throughout the NHS.
BMJDIPHTHERIA IN THE DUNEDIN HOSPITAL, 1921-31: A STATISTICAL AND CLINICAL STUDY
2 Citations1932C. E. Hercus, H. Wilson
Sources: Ramage, H., and Sheldon, J. H., Nature, August 29th, 1931; Kemmerer, A. R., and Todd, W. C.