Lymphatic Filariasis Control in Tanzania: Effect of Repeated Mass Drug Administration with Ivermectin and Albendazole on Infection and Transmission
PLoS neglected tropical diseasesPublished 1 June 2010Open access
Paul E. Simonsen, Erling M Pedersen, Rwehumbiza T. Rwegoshora, Mwelecele N. Malecela, Yahya A. Derua, Stephen Magesa
Citations120
SJR quartileQ1
SJR score1.37
SNIP1.44
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TL;DR
The findings highlight the importance of ongoing surveillance for monitoring the progress of LF control programmes, and calls for more research into the long-term effect of repeated ivermectin/albendazole MDAs (including the significance of treatment intervals and compliance), in order to optimize efforts to control LF in sub-Saharan Africa.
Abstract
Critical issues that may potentially explain the observed waning effect of the MDAs in the later study period include the long intervals between MDAs and a lower than optimal treatment coverage. The findings highlight the importance of ongoing surveillance for monitoring the progress of LF control programmes, and it calls for more research into the long-term effect of repeated ivermectin/albendazole MDAs (including the significance of treatment intervals and compliance), in order to optimize efforts to control LF in sub-Saharan Africa.
Keywords
Immunology and MicrobiologyMedicineEnvironmental Science
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