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Interacting Effects of the Dopamine Transporter Gene and Psychosocial Adversity on Attention-Deficit/Hyperactivity Disorder Symptoms Among 15-Year-Olds From a High-Risk Community Sample

Archives of General PsychiatryPublished 1 May 2007
Manfred Laucht, Markus H. Skowronek, Katja Becker, Martin H. Schmidt, Günter Esser, Thomas G. Schulze
Citations204

TL;DR

Findings provide initial evidence that environmental risks as described by the Rutter Family Adversity Index moderate the impact of the DAT1 gene on ADHD symptoms, suggesting a Dat1 effect only in those individuals exposed to psychosocial adversity.

Abstract

These findings provide initial evidence that environmental risks as described by the Rutter Family Adversity Index moderate the impact of the DAT1 gene on ADHD symptoms, suggesting a DAT1 effect only in those individuals exposed to psychosocial adversity.

Keywords

PsychologyMedicine