HIV prevention: an update on the status of methods women can use.
American Journal of Public HealthPublished 1 October 1993Open access
Zena Stein
Citations63
SJR quartileQ1
SJR score1.93
SNIP1.60
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TL;DR
While awaiting the development of longterm microbicides or vaccines the largely untested efficacy of barrier methods for prevention needs to be moved from the area of speculation to a central position in research studies.
Abstract
HIV prevention: an update on the status of methods women can use. Z SteinCopyRight https://doi.org/10.2105/AJPH.83.10.1379 Published Online: October 07, 2011
Keywords
Immunology and MicrobiologyMedicineHealth Professions
PubMedEpidemiological synergy. Interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases.
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AIDSNon-ulcerative sexually transmitted diseases as risk factors for HIV-1 transmission in women
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753 Citations1989D. William Cameron, LourdesJ D'Costa +9 more
Data indicate an extremely high rate of female to male transmission of HIV-1 in the presence of STD and confirm a causal relation between lack of male circumcision, genital ulcer disease, and susceptibility to HIV- 1 infection.
The Journal of Infectious DiseasesCofactors in Male-Female Sexual Transmission of Human Immunodeficiency Virus Type 1
712 Citations1991FA Plummer, J. Neil Simonsen +9 more
Stepwise logistic regression analysis confirmed independent associations between HIV-1 infection and oral contraceptive use, condom use, genital ulcers, and C. trachomatis, and the presence of other sexually transmitted diseases may in part explain the heterosexual HIV- 1 epidemic in Africa.
JAMAEfficacy of Nonoxynol 9 Contraceptive Sponge Use in Preventing Heterosexual Acquisition of HIV in Nairobi Prostitutes
392 Citations1992Joan K. Kreiss
It was unable to demonstrate that nonoxynol 9 sponge use was effective in reducing the risk of HIV infection among highly exposed women.
American Journal of Public HealthHIV prevention: the need for methods women can use.
381 Citations1990Zena Stein
Greater emphasis is urged for research on preventive methods women could use, including the possibility of a topical virucide that might block transmission through the vaginal route.
Family Planning PerspectivesFamily Planning, Sexually Transmitted Diseases and Contraceptive Choice: A Literature Update--Part II
224 Citations1992Willard Cates, Katherine M. Stone
PubMedMan-to-woman sexual transmission of HIV: longitudinal study of 343 steady partners of infected men.
198 Citations1993A. Saracco, Massimo Musicco +8 more
The Journal of Infectious DiseasesA Clinical Trial of Nonoxynol-9 for Preventing Gonococcal and Chlamydial Infections
137 Citations1988William C. Louv, Harland Austin +3 more
A randomized, double-blind, placebo-controlled trial was conducted to evaluate the spermicidal agent nonoxynol-9 as prophylaxis for cervical infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae.
American Journal of Public HealthBarrier contraceptives and sexually transmitted diseases in women: a comparison of female-dependent methods and condoms.
133 Citations1992M. J. Rosenberg, Ange Davidson +3 more
Women using the contraceptive sponge or diaphragm experience protection from STDs to a greater extent than those relying on condoms, and female-dependent barrier contraceptives should receive more attention in STD risk-reduction programs.
American Journal of Public HealthCommentary: methods women can use that may prevent sexually transmitted disease, including HIV.
131 Citations1992M. J. Rosenberg, Erica L. Gollub
The imperative for female-controlled methods indicates that diaphragms and spermicides should receive greater emphasis in prevention messages, because those methods that are controlled by women are consistently more effective in preventing sexually transmitted diseases.
AIDSEpidemiological methods to study the interaction between HIV infection and other sexually transmitted diseases
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Special emphasis is given to the use of randomized intervention trials to overcome many of the biases associated with observational studies, and to provide information on the efficacy of intensive STD treatment programmes in reducing the transmission of HIV.
JAIDS Journal of Acquired Immune Deficiency SyndromesMan-To-Woman Sexual Transmission of HIV
115 Citations1993Alberto Saracco, Massimo Musicco +19 more
A cohort of 343 seronegative women, stable, monogamous partners of infected men whose only risk of acquiring HIV was sexual exposure to the infected partner, followed to study incidence and risk factors of heterosexually transmitted HIV infection.
Fertility and SterilitySexual transmission of human immunodeficiency virus: virus entry into the male and female genital tract
114 Citations1990Edward E. Wallach, Nancy J. Alexander
Research is needed to determine the site of entry of HIV into reproductive tissues risks throughout the menstrual cycle and protective effects of contraceptives as result of this knowledge.
BMJEpidemiology and clinical significance of cervical erosion in women attending a family planning clinic.
104 Citations1978Michael J Goldacre, N Loudon +5 more
Cervical erosion should not be regarded as pathological in asymptomatic women, nor should it be assumed necessarily to be the cause of symptoms in women with genitourinary complaints.
JAMAEfficacy of nonoxynol 9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes
104 Citations1992J. Kreiss
The LancetUse of nonoxynol-9 and reduction in rate of gonococcal and chlamydial cervical infections
101 Citations1992Somchai Niruthisard, Supawat Chutivongse +1 more
The use of a vaginal N-9 spermicide with condoms whenever possible seems to be a better strategy than the use of condoms only for prevention of gonococcal and chlamydial cervical infection.
The Journal of PediatricsDifferences in biologic maturation, sexual behavior, and sexually transmitted disease between adolescents with and without cervical intraepithelial neoplasia
100 Citations1989Anna‐Barbara Moscicki, Barbara Winkler +2 more
AIDSBarrier contraceptive use and HIV infection among high-risk women in Cameroon
96 Citations1993Léopold Zekeng, Paul J. Feldblum +2 more
This is the first epidemiological evidence that N-9 spermicides can reduce the incidence of HIV infection, and a more definitive randomized clinical trial is urgently needed.
The development of microbicides: A new method of HIV prevention for women
59 Citations1993Christopher Elias, Lori Heise
The growing risk of HIV infection faced by women throughout the world is described and the serious limitation of contemporary AIDS prevention strategy in meeting the needs of women is examined; the existing data on female-controlled HIV prevention mehtods are reviewed; and the challenges for future microbicide development are outlined.
The Public Health Significance of Sexually Transmitted Diseases for HIV Infection in Africa
9 Citations1991Seth Berkley
In sub-Saharan Africa, the primary mode of transmission of HIV is through heterosexual intercourse, and scientists and public health officials have called for the urgent enhancement of existing STD programs, or implementation of new programs, as an important strategy in AIDS prevention.