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The Anatomy of Brain Stem Pathways to the Spinal Cord in Cat. A Labeled Amino Acid Tracing Study

Progress in brain researchPublished 1 January 1982
Gert Holstege, H.G.J.M. Kuypers
Citations553

TL;DR

The brain stem distribution of the cells of origin of these pathways in the cat has been reinvestigated by means of the horseradish peroxidase (HRP) technique by using the procedure of Mesulam to facilitate the identification of the various descending pathways.

Abstract

This chapter discusses the anatomy of brain stem pathways to the spinal cord in cat. In the series of experiments described in the chapter, [3H] leucine injections were made in the brain stem and the spinal distribution of the labeled descending brain stem pathways was studied autoradiographically. The pontine reticulospinal tract, as well as the vestibulospinal tracts, distribute to the ventromedial parts of the intermediate zone mainly ipsilaterally. Anterograde fiber degeneration findings obtained since the early decades of this century by means of several techniques consistently showed that the descending brain stem pathways to the spinal cord terminate mainly in the spinal intermediate zone—for example, in Rexed's laminae V–VIII. However, to facilitate the identification of the various descending pathways, the brain stem distribution of the cells of origin of these pathways in the cat has been reinvestigated by means of the horseradish peroxidase (HRP) technique by using the procedure of Mesulam.

Keywords

MedicineNeuroscience