Simple Allosteric Model for Membrane Pumps

It appears timely to point out that transport contingent on a chemical reaction can be understood in terms of a very simple molecular model, for which a noteworthy precedent can be found among recent crystal structure determinations.

Abstract

THE list of plausible hypothetical schemes which have been advanced to account for active transport is so long that any hope of extending it might appear unwarranted. However, very few specific molecular mechanisms have been considered. It therefore appears timely to point out that transport contingent on a chemical reaction can be understood in terms of a very simple molecular model, for which a noteworthy precedent can be found among recent crystal structure determinations.