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Effects of Initiating Carvedilol in Patients With Severe Chronic Heart Failure

JAMAPublished 12 February 2003Open access
Henry Krum, Ellen B. Roecker, Paul Mohaçsi, Jean L. Rouleau, Michał Tendera, Andrew J.S. Coats
Citations307
SJR quartileQ1
SJR score5.35
SNIP10.71
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Abstract

These data suggest that, in clinically euvolemic patients, the relation of benefit to risk during initiation of treatment with carvedilol is similar to that seen during long-term therapy with the drug. Our findings should provide the reassurance needed to encourage the high levels of use that are warranted by the results of long-term clinical trials.

Keywords

Medicine