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II. New evidence for a locus coeruleus-norepinephrine connection with anxiety

Life SciencesPublished 1 December 1979
D. Eugene Redmond, Y.H. Huang
Citations666
SJR quartileQ1
SJR score1.31
SNIP1.07

TL;DR

Data from studies of the function of the nucleus locus coereleus in non-human primates are presented in the context of recent anatomical, physiological, pharmacological, and animal behavioral experiments, suggesting implications for the treatment of anxiety, drug addictions, pain, and psychosomatic diseases.

Abstract

The hypothesis that brain noradrenergic systems have a broad biological function which is related to human fear or anxiety is reviewed. Data from studies of the function of the nucleus locus coereleus in non-human primates are presented in the context of recent anatomical, physiological, pharmacological, and animal behavioral experiments. Implications are suggested for the treatment of anxiety, drug addictions, pain, and psychosomatic diseases.

Keywords

PsychologyNeuroscienceBiochemistry, Genetics and Molecular Biology