Evidence-based management options for women at increased breast/ovarian cancer risk
Annals of OncologyPublished 17 December 2002Open access
Gabriella Pichert, B. Bolliger, K. Buser, Olivia Pagani
Citations56
SJR quartileQ1
SJR score19.07
SNIP10.48
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TL;DR
Management options are given for women at slightly, moderately and highly elevated breast cancer risk, as well as for BRCA1/2 carriers, based on currently available evidence.
Abstract
Recent developments in our ability to predict breast cancer risk necessitates primary care physicians learn to evaluate breast cancer risk and its importance in shaping decisions concerning surveillance and risk reduction measures. This article reviews the current opinion on risk assessment and management of women with an increased risk of breast/ovarian cancer. Management options are given for women at slightly, moderately and highly elevated breast cancer risk, as well as for BRCA1/2 carriers, based on currently available evidence.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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27 Citations1986Lennart Meyer, Anita Ringberg
Short- and long-term adaptation to bilateral subcutaneous mastectomy was studied in twenty-five consecutive patients operated upon at the Department of Plastic and Reconstructive Surgery, Malmö, Sweden.
American Journal of RoentgenologyMammography of breast carcinoma in women who have mutations of the breast cancer gene BRCA1: initial experience.
26 Citations1997M A Helvie, Marilyn A. Roubidoux +2 more
The mammographic appearance of breast cancer in BRCA1 carriers was similar to that in the general population and appropriate mammographic management of these extremely high-risk patients is yet to be determined.
The LancetMammography in Asian patients with BRCA1 mutations
25 Citations1999Joyce C. Chang, WT Yang +1 more
PubMedInherited predisposition to breast carcinoma. Results of first round examination of 537 women at risk.
20 Citations1996Anna Barbro Sætersdal, Anne Dørum +7 more
It is suggested that atypical hyperplasia may be the precancerous lesion, and should be treated as such in women at risk for breast carcinoma.
Clinics in Plastic SurgeryProphylactic Mastectomy with Immediate Reconstruction for the High-Risk Woman
16 Citations1984Robert Leonard
The procedure of choice described here removes the nipple-areola complex, thins and cores it, and replaces it as a free graft when the breast parenchyma is removed.
PubMedOrganizing cancer genetics programs: the Swiss model.
12 Citations2000Gabriella Pichert, Rolf A. Stahel
A coordinated effort will ensure state-of-the-art genetic testing and counseling services in Switzerland and will allow us to acquire knowledge for appropriate risk assessment and surveillance/prevention strategies for individuals with an inherited cancer predisposition.
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