Relationship of HIV Viral Loads, CD4 Counts, and HAART Use to Health-Related Quality of Life
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TL;DR
In this analysis, HAART had negative effects on PF that were independent of its effects on CD4 and VL that are likely to be outweighed by the positive effects that HAART exerts through lowering VL and increasing CD4 counts.
Abstract
Efforts to improve patients' CD4 counts are likely to also improve HRQL. Lowering viral loads may improve physical functioning, but only if VL are suppressed to undetectable levels. In this analysis, HAART had negative effects on PF that were independent of its effects on CD4 and VL. For adherent patients, these adverse effects of HAART on PF are likely to be outweighed by the positive effects that HAART exerts through lowering VL and increasing CD4 counts.
