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Relationship of HIV Viral Loads, CD4 Counts, and HAART Use to Health-Related Quality of Life

JAIDS Journal of Acquired Immune Deficiency SyndromesPublished 1 August 2002
Christopher Gill, John L. Griffith, Denise L. Jacobson, Sarah Skinner, Sherwood L. Gorbach, Ira B. Wilson
Citations121
SJR quartileQ1
SJR score1.04
SNIP0.81

TL;DR

In this analysis, HAART had negative effects on PF that were independent of its effects on CD4 and VL that are likely to be outweighed by the positive effects that HAART exerts through lowering VL and increasing CD4 counts.

Abstract

Efforts to improve patients' CD4 counts are likely to also improve HRQL. Lowering viral loads may improve physical functioning, but only if VL are suppressed to undetectable levels. In this analysis, HAART had negative effects on PF that were independent of its effects on CD4 and VL. For adherent patients, these adverse effects of HAART on PF are likely to be outweighed by the positive effects that HAART exerts through lowering VL and increasing CD4 counts.

Keywords

Immunology and MicrobiologyMedicine