Potentiation of Cocaine-Induced Coronary Vasoconstriction by Beta-Adrenergic Blockade
Annals of Internal MedicinePublished 15 June 1990
Richard A. Lange, Ricardo G. Cigarroa, Eduardo D. Flores, Wade McBride, Anatole S. Kim, Peter J. Wells
Citations415
SJR quartileQ1
SJR score3.38
SNIP3.27
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TL;DR
Beta-adrenergic blocking agents probably should be avoided in patients with cocaine-associated myocardial ischemia or infarction because they potentiate cocaine-induced coronary vasoconstriction, which is potentiated by beta- adrenergic blockade.
Abstract
Cocaine-induced coronary vasoconstriction is potentiated by beta-adrenergic blockade. Beta-adrenergic blocking agents probably should be avoided in patients with cocaine-associated myocardial ischemia or infarction.
Keywords
Medicine
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Treating the seizures with diazepam and treatment of the acidosis with ventilation and bicarbonate can normalize cardiac rhythm and function in these critically ill patients.
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156 Citations1985Louis L. Cregler, Herbert Mark
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139 Citations1986Rosi Simpson, William D. Edwards
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JAMAAcute Myocardial Infarction Following Cocaine Abuse in a Young Woman With Normal Coronary Arteries
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CHEST JournalCocaine and Acute Myocardial Infarction
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131 Citations1985Peter F. Pasternack, Stephen B. Colvin +1 more
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These results are in excellent agreement with cocaine tissue distribution in the dog following IV administration and limited tissue data in previously reported cocaine fatalities in man.
Archives of OphthalmologyCocaine Toxicity During Dacryocystorhinostomy
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Postgraduate Medical JournalCardiac arrhythmia and myocardial ischaemia related to cocaine and alcohol consumption
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