Cocaine-induced Churg-Strauss vasculitis
European Respiratory JournalPublished 1 January 1996Open access
Ramón Orriols, Xavier Muñoz, J.M. Escribano Ferrer, P. Huget, Ferrán Morell
Citations86
SJR quartileQ1
SJR score4.50
SNIP3.47
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
A freebase cocaine-smoking woman developed relapsing fever, bronchoconstriction, arthralgias and weight loss, and it is suggested that Churg-Strauss vasculitis may be a complication of smokingfreebase cocaine.
Abstract
A freebase cocaine-smoking woman developed relapsing fever, bronchoconstriction, arthralgias and weight loss. Pulmonary infiltrates, arthritis, microhaematuria, pruriginous skin rash and mononeuritis multiplex were later added to the clinical picture. Both skin and muscle biopsies showed eosinophilic angiitis. Improvement or worsening of her clinical picture repeatedly coincided with avoidance or use of smoked cocaine, respectively. We suggest that Churg-Strauss vasculitis may be a complication of smoking freebase cocaine.
Keywords
Medicine
MedicineSystemic Vasculitis with Asthma and Eosinophilia
1,239 Citations1984John Lanham, Keith B. Elkon +2 more
NeurologyBiopsy‐proven cerebral vasculitis associated with cocaine abuse
173 Citations1990David A. Krendel, Susan M. Ditter +2 more
JAMACerebral vasculitis associated with cocaine abuse
147 Citations1987Brian R. Kaye
Cocaine with methamphetamines, heroin, and ephedrine are included in the list of illicit drugs that can cause cerebral vasculitis in men with a history of cocaine abuse.
American Review of Respiratory DiseaseCrack Lung: Pulmonary Disease Caused by Cocaine Abuse
128 Citations1987Dana G. Kissner, W. Dwayne Lawrence +2 more
A patient developed 3 separate episodes of fever, transient pulmonary infiltrates, and bronchospasm after inhalation of cocaine, indicating an immunologic pathogenetic mechanism.
CHEST JournalDiffuse Alveolar Hemorrhage Temporally Related to Cocaine Smoking
118 Citations1988Richard J. Murray, Robert J. Albin +2 more
A patient who developed life-threatening alveolar hemorrhage following repeated inhalation of alkaloid cocaine is reported, indicating a reduction in carbon monoxide diffusing capacity.
The American Journal of MedicineA review of the respiratory effects of smoking cocaine
111 Citations1989Neil Ettinger, Robert J. Albin
A variety of pulmonary complications related to the use of freebase cocaine have been reported in the medical literature, and the roles of either cocaine, tobacco, or adulterants in producing the observed abnormalities of lung function remain controversial.
LungSystemic necrotizing angiitis with asthma: Causes and precipitating factors in 43 cases
110 Citations1987Loı̈c Guillevin, T Guittard +3 more
It is suggested that different causes can be considered responsible for NA, and that, in cases of NA with asthma, there is reason to consider vaccination and desensitization as precipitating factors.
The American Journal of MedicineOnset of polyarteritis nodosa during allergic hyposensitization treatment
90 Citations1980Praphan Phanuphak, Peter F. Köhler
When compared with the 14 other patients with polyarteritis nodosa, those undergoing hyposensitization had significantly greater skin involvement and peripheral blood eosinophilia and evidence for circulating immune complexes with decreased hemolytic complement, increased cryoglobulins or increased Clq binding was present in both groups.
ThoraxCocaine induced eosinophilic lung disease.
65 Citations1992Patrick Oh, Meyer Balter
A patient developed fever, bronchoconstriction, hypoxaemia, pulmonary infiltrates, and serum and bronchoalveolar lavage fluid eosinophilia on two occasions after inhaling crack cocaine.
CHEST JournalChurg-Strauss Angiitis
33 Citations1991Loı̈c Guillevin, Jacques Atnouroux +2 more
A 27-year-old man presented with relapsing vascular limb purpura, pulmonary infiltrates and cranial nerve palsies occurring after exposure to pigeons, and a lung biopsy specimen showed Churg-Strauss angiitis.
CHEST JournalLöffler's Syndrome Secondary to Crack Cocaine
32 Citations1994Sabha Nadeem, Nadeem Nasir +1 more
Annals of the Rheumatic DiseasesChurg-Strauss vasculitis and ascaris infection.
26 Citations1990Abhishek Chauhan, David G. I. Scott +3 more
A patient with Churg-Strauss vasculitis presenting with mononeuritis multiplex, who developed obstructive jaundice, is described, which proved to be due to ascaris infestation.
PubMedAccelerated atherosclerosis, aneurysmal disease, and aortitis: possible pathogenetic association with cocaine abuse.
24 Citations1992Bacharach Jm, Colville Ds +1 more
A case of diffuse aneurysmal change of the aorta associated with an atypical inflammatory component consistent with possible cocaine induced vasculitis is reported.
The American Journal of MedicineA review of the respiratory effects of smoking cocaine
4 Citations1989Neil Ettinger, Robert J. Albin