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Regionalization in the mammalian telencephalon

Current Opinion in NeurobiologyPublished 1 February 1997Open access
Gord Fishell
Citations41
SJR quartileQ1
SJR score2.54
SNIP1.27
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TL;DR

The mechanisms underlying the commitment of telencephalic cells to specific regional identities have been examined through recent transplantation experiments and suggest subdivisions arise relatively late in development compared with the spinal cord or hindbrain.

Abstract

Regionalization in the telencephalon results in the formation of functionally and anatomically distinct territories. Cell fate analysis and gene expression studies suggest these subdivisions arise relatively late in development compared with the spinal cord or hindbrain. The mechanisms underlying the commitment of telencephalic cells to specific regional identities have been examined through recent transplantation experiments.

Keywords

NeuroscienceBiochemistry, Genetics and Molecular Biology