Proteins
BioengineeredPublished 1 March 2012Open access
Roy D. Sleator
Citations17
SJR quartileQ1
SJR score1.05
SNIP0.88
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TL;DR
The primary mechanisms which have contributed to the vastness of the existing, and expanding, protein repertoires are reviewed.
Abstract
An overwhelming array of structural variants has evolved from a comparatively small number of protein structural domains; which has in turn facilitated an expanse of functional derivatives. Herein, I review the primary mechanisms which have contributed to the vastness of our existing, and expanding, protein repertoires. Protein function prediction strategies, both sequence and structure based, are also discussed and their associated strengths and weaknesses assessed.
Keywords
Biochemistry, Genetics and Molecular Biology
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