Impairment and Deportment Responses to Different Methylphenidate Doses in Children With ADHD: The MTA Titration Trial
Journal of the American Academy of Child & Adolescent PsychiatryPublished 1 February 2001
LAURENCE L. GREENHILL, James M. Swanson, BENEDETTO VITIELLO, Mark Davies, Walter Clevenger, Min Wu
Citations290
SJR quartileQ1
SJR score3.00
SNIP2.88
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TL;DR
The MTA titration protocol validated the efficacy of weekend MPH dosing and established a total daily dose limit of 35 mg of MPH for children weighing less than 25 kg.
Abstract
The MTA titration protocol validated the efficacy of weekend MPH dosing and established a total daily dose limit of 35 mg of MPH for children weighing less than 25 kg. It replicated previously reported MPH response rates (77%), distribution of best doses (10-50 mg/day) across subjects, effect sizes on impairment and deportment, as well as dose-related adverse events.
Keywords
PsychologyMedicine
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