Distributed, intelligent, interactive visualization and exploration of time-oriented clinical data and their abstractions
Artificial Intelligence in MedicinePublished 19 December 2005
Yuval Shaḥar, Dina Goren‐Bar, David Boaz, Gil Tahan
Citations119
SJR quartileQ1
SJR score1.40
SNIP1.93
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Initial evaluation of KNAVE-II and its supporting knowledge based temporal-mediation architecture, by applying it to a large data base of patients monitored several years after bone marrow transplantation (BMT), has produced highly encouraging results.
Abstract
Initial evaluation of KNAVE-II and its supporting knowledge based temporal-mediation architecture, by applying it to a large data base of patients monitored several years after bone marrow transplantation (BMT), has produced highly encouraging results.
Keywords
Computer ScienceHealth Professions
Modern Information Retrieval
11,544 Citations1999Ricardo Baeza‐Yates, Berthier Ribeiro‐Neto
Springer series in information sciencesSelf-Organizing Maps
10,377 Citations1997Teuvo Kohonen
The mathematical preliminaries, background, basic ideas, and implications of the Self-Organising Map algorithm are expounded in a manner which is accessible without prior expert knowledge.
Usability Engineering
9,352 Citations1993Jakob Nielsen
SUS: A 'Quick and Dirty' Usability Scale
8,122 Citations1996john Brooke
Applied ErgonomicsDesigning the user interface: Strategies for effective human-computer interaction
5,616 Citations1993
Readings in Information Visualization: Using Vision to Think
3,967 Citations1999Stuart K. Card, Jock D. Mackinlay +1 more
Cognitive ScienceWhy a Diagram is (Sometimes) Worth Ten Thousand Words
3,579 Citations1987Jill H. Larkin, Herbert A. Simon
Artificial IntelligenceTowards a general theory of action and time
2,562 Citations1984James F. Allen
A formalism for reasoning about actions that is based on a temporal logic allows a much wider range of actions to be described than with previous approaches such as the situation calculus and a framework for planning in a dynamic world with external events and multiple agents is suggested.
ACM SIGBIO NewsletterDesigning the user interface strategies for effective human-computer interaction
1,731 Citations1987Ben Shneiderman
The Sixth Edition of Designing the User Interface provides a comprehensive, authoritative, and up-to-date introduction to the dynamic field of human-computer interaction (HCI) and user experience (UX) design.
Reexamining the cluster hypothesis
828 Citations1996Marti A. Hearst, Jan Pedersen
This work systematically evaluates Scatter/Gather in this context and finds significant improvements over similarity search ranking alone and provides evidence validating the cluster hypothesis which states that relevant documents tend to be more similar to each other than to non-relevant documents.
Visual information seeking
824 Citations1994Christopher Ahlberg, Ben Shneiderman
Cognitive ScienceA temporal logic for reasoning about processes and plans
760 Citations1982Drew McDermott
Computers & Mathematics with ApplicationsThe invisible computer: Why good products can fail, the personal computer is so complex and information appliances are the solution
601 Citations1999Donald A. Norman
LifeLines: visualizing personal histories
586 Citations1996Catherine Plaisant, Brett Milash +3 more
The paper describes the use of LifeLines for youth records of the Maryland Department of Juvenile Justice and also for medical records, and Techniques to deal with complex records are reviewed and issues of a standard personal record format are discussed.
IEEE SoftwareDynamic queries for visual information seeking
569 Citations1994B. Shneiderman
The author discusses how experts may benefit from visual interfaces because they will be able to formulate more complex queries and interpret intricate results.
ACM Transactions on Computer-Human InteractionA review and taxonomy of distortion-oriented presentation techniques
499 Citations1994Yuet‐Kin Leung, Mark Apperley
This article provides a taxonomy of distortion-oriented techniques which demonstrates clearly their underlying relationships and a unified theory is presented to reveal their roots and origins.
Cognitive ScienceA Temporal Logic for Reasoning about Processes and Plans*
493 Citations1982Drew McDermott
A first-order temporal logic, in which it is possible to name and prove things about facts, events, plans, and world histories, and provides analyses of causality, continuous change in quantities, the persistence of facts, and the relationship between tasks and actions.
Artificial IntelligenceA framework for knowledge-based temporal abstraction
456 Citations1997Yuval Shaḥar
A new domain-independent knowledge-based inference structure is presented, specific to the task of abstracting higher-level concepts from time-stamped data, and has been evaluated in several clinical domains and in an engineering domain, with encouraging results.
Artificial Intelligence in MedicineThe Asgaard project: a task-specific framework for the application and critiquing of time-oriented clinical guidelines
450 Citations1998Yuval Shaḥar, Silvia Miksch +1 more
This paper points out the precise domain-specific knowledge required by each method, such as the explicit intentions of the guideline designer, and presents a machine-readable language, called Asbru, to represent and to annotate guidelines based on the task-specific ontology.
Elsevier eBooksLifeLines: Using Visualization to Enhance Navigation and Analysis of Patient Records
365 Citations2003Catherine Plaisant, Richard Mushlin +4 more
A Java user interface is described, which presents a one-screen overview of a computerized patient record using timelines using LifeLines, which acts as a giant menu, giving direct access to the data.
Journal of the American Medical Informatics AssociationEON: A Component-Based Approach to Automation of Protocol-Directed Therapy
347 Citations1996Mark A. Musen, Samson W. Tu +2 more
A synthesis of research carried out at Stanford University to model the therapy-planning task and to demonstrate a component-based architecture for building protocol-based decision-support systems is presented.
Computers and Biomedical ResearchAn analysis of physician attitudes regarding computer-based clinical consultation systems
333 Citations1981Randy L. Teach, Edward H. Shortliffe
Physician attitudes regarding computer-based clinical decision aids and the effect of a 2-day tutorial on medical computing are studied, indicating that physicians are accepting of applications that enhance their patient management capabilities, but tend to oppose applications in which they perceive an infringement on their management role.
Artificial Intelligence in MedicineKnowledge-based temporal abstraction in clinical domains
315 Citations1996Yuval Shaḥar, Mark A. Musen
A knowledge-based framework for the creation of abstract, interval-based concepts from time-stamped clinical data, the knowledge- based temporal-abstraction (KBTA) method is defined and the RESUME system implements the KBTA method.
Journal of Visual Languages & ComputingPad++: A Zoomable Graphical Sketchpad For Exploring Alternate Interface Physics
315 Citations1996Benjamin B. Bederson, James D. Hollan +4 more
A rich world of dynamic persistent informational entities that operate according to multiple physics specifically designed to provide cognitively facile access and serve as the basis for design of new computationally-based work materials is envisioned.
Journal of the American Society for Information ScienceInternet browsing and searching: User evaluations of category map and concept space techniques
274 Citations1998Hsinchun Chen, Andrea L. Houston +2 more
The results indicate that a Kohonen self-organizing map (SOM)-based algorithm can successfully categorize a large and eclectic Internet information space into manageable sub-spaces that users can successfully navigate to locate a homepage of interest to them.
Artificial IntelligenceTemporal logics in AI: Semantical and ontological considerations
267 Citations1987Yoav Shoham
This paper examines this method by looking closely at two of the more influential formalisms featuring reified propositions, those of Allen and McDermott, and presents a new formalism that does not suffer from these disadvantages.
Medical Entomology and ZoologyUser Centered Design: An Integrated Approach
255 Citations2001Karel Vredenburg, Scott Isensee +1 more
This book discusses the Integrated Approach to UCD, which aims to provide Universal Access with UCD by addressing the primary targets of education, performance support, Organizational Learning and Multidisciplinary Communication and Collaboration.
Journal of the American Society for Information ScienceInternet browsing and searching: User evaluations of category map and concept space techniques
177 Citations1998Hsinchun Chen, Andrea L. Houston +2 more
IVEE: an Information Visualization and Exploration Environment
168 Citations2002C. Ahlberg, Erik Wistrand
The Information Visualization and Exploration Environment (NEE) is a system for automatic creation of dynamic queries applications that offers multiple visualizations such as maps and starfields, and multiple query devices, such as sliders, alphasliders, and toggles.
Visualizing digital library search results with categorical and hierarchical axes
160 Citations2000Ben Shneiderman, David Feldman +2 more
A simplified two-dimensional display that uses categorical and hierarchical axes, called hieraxes, that is applied to a digital video library of science topics used by middle school teachers, a legal information system, and a technical library using the ACM Computing Classification System.
IEEE SoftwareReuse in Command-and-Control Systems
130 Citations1994Jennifer B. O'Connor, C. Mansour +2 more
This work presents CCSD's experience to date using Synthesis, an approach based on domain-specific reuse, by which an organization can standardize its perceptions of customers' needs and effective solutions.
Intelligent Data Analysis in Medicine and Pharmacology
129 Citations1997Nada Lavrač, Elpida Keravnou +1 more
Much of the presented material will be interesting to physicians and pharmacologists challenged by new computational technologies, or simply in need of effectively utilizing the overwhelming volumes of data collected as a result of improved computer support in their daily professional practice.
AI MagazineCollaborative Systems (AAAI-94 Presidential Address)
118 Citations1996Barbara J. Grosz
It is argued that collaboration must be designed into systems from the start; it cannot be patched on and research on, and the development of, collaborative systems should itself be a collaborative endeavor.
Artificial Intelligence in MedicineInformation visualization and its application to medicine
113 Citations2001Luca Chittaro
This paper provides an introduction to the field of information visualization and a discussion of its application to medical systems by defining what IV is and what are its goals.
Artificial Intelligence in MedicineThe visual display of temporal information
108 Citations1991Steve Cousins, Michael G. Kahn
This work presents a formal system for representing complex temporal data as events on an abstract entity called a time line, and describes an interactive environment designed specifically to help humans visualize temporal data.
European Journal of Operational ResearchHigh interaction graphics
83 Citations1995Stephen G. Eick, Graham Wills
The core features of interactive Graphics are discussed, how familiar plots can be made interactive and examples of interactive graphics for general and specific data analysis are shown.
Design issues in adaptive web-site development
78 Citations1999P.M.E. De Bra
This paper sketches a general architecture for adaptive Web-sites by building on existing models such as Dexter and IMMPS, and identifies issues in adaptive web-site design for which no general approach or solution appears to exist.
Automated trend detection with alternate temporal hypotheses
76 Citations1993Ira J. Haimowitz, Isaac S. Kohane
A prototype computer program called TrenDx is written for automated trend detection during process monitoring and reaches temporally plausible diagnoses for an actual patient with delayed growth currently being seen at Boston Children's Hospital.
Prentice Hall PTR eBooksUser-Centered Design: An Integrated Approach with Cdrom
70 Citations2001Karel Vredenberg, Scott Isensee +1 more
This book provides an integrated approach to User-Centered Design with an emphasis on using UCD to make products easy to buy, learn, and use and focuses on designing a compelling "total customer experience"everything a customer sees, hears, and touches about a product or system.
Methods of Information in MedicineCombining Physiologic Models and Symbolic Methods to Interpret Time-Varying Patient Data*
69 Citations1991Michael G. Kahn, L M Fagan +1 more
A program, called TOPAZ, that uses a three-step methodology for representing and using medical knowledge about temporal relationships to infer the presence of clinical events that evolve over time and generates a narrative summary of the temporal events found in the electronic medical record of patients receiving cancer chemotherapy.
DSpace@MIT (Massachusetts Institute of Technology)TEMPORAL REASONING IN MEDICAL EXPERT SYSTEMS
67 Citations1987Isaac S. Kohane
TUP and THRIPHT together illustrate why temporal reasoning is necessary for successful second generation medical expert systems, and how to provide this capability.
Artificial Intelligence in MedicineA study of collaboration among medical informatics research laboratories
62 Citations1998Edward H. Shortliffe, Vimla L. Patel +3 more
Artificial Intelligence in MedicineA framework for distributed mediation of temporal-abstraction queries to clinical databases
54 Citations2005David Boaz, Yuval Shaḥar
The implemented IDAN architecture proves the feasibility of the distributed integration of medical knowledge sources with clinical data of heterogeneous sources and suggests that the proposed IDAN modular architecture has potential significance for supporting the automation of clinical tasks such as diagnosis, monitoring, therapy, and quality assessment.
Annals of Mathematics and Artificial IntelligenceDynamic temporal interpretation contexts for temporal abstraction
50 Citations1998Yuval Shaḥar
The logical model underlying the representation and runtime formation of interpretation contexts, a formal knowledge‐based framework for decomposing and solving that task that supports acquisition, maintenance, reuse, and sharing of temporal‐abstraction knowledge is presented.
Intelligent visualization and exploration of time-oriented clinical data
48 Citations2003Yuval Shaḥar, Cleve Cheng
The new framework KNAVE (Knowledge-based Navigation of Abstractions for Visualization and Explanation) has broad ramifications for reducing the load that large numbers of time oriented clinical data put on practising physicians.
Artificial Intelligence in MedicineInformation visualisation in clinical Odontology: multidimensional analysis and interactive data exploration
46 Citations2001Göran Falkman
Two information visualisation tools were developed and tested as solutions to the problem of visualising clinical experience derived from large amounts of clinical data, one based on the idea of dynamic three-dimensional parallel diagrams and the other on a similarity assessment-based interaction model.
Artificial Intelligence in MedicineVisualization and interactive analysis of blood parameters with InfoZoom
44 Citations2001Michael Spenke
This paper describes the application of the data analysis tool InfoZoom to a database containing the results of blood examinations for about 400 patients with a suspect of thrombosis, to find correlations between the measurements and the occurrence of a thromBosis.
Journal of Intelligent Information SystemsIntegration of Temporal Reasoning and Temporal-Data Maintenance into a Reusable Database Mediator to Answer Abstract, Time-Oriented Queries: The Tzolkin System
41 Citations1999John H. Nguyen, Yuval Shaḥar +3 more
Tzolkin allows clinicians to use SQL-like temporal queries to retrieve both raw, time-oriented data and dynamically generated summaries of those data, and decreases the cost of building new software systems that require this functionality.
Methods of Information in MedicineManaging Different Time Granularities of Clinical Information by an Interval-based Temporal Data Model
40 Citations1995Francesco Pinciroli, Giuseppe Pozzi +1 more
An object-oriented database system for managing follow-up clinical data from patients who underwent percutaneous transluminal coronary angioplasty is implemented by implementing a temporal data model that allows to manage some degrees of uncertainty when establishing temporal relationships between intervals or between temporal assertions.
Computational IntelligenceModel‐Based Visualization of Temporal Abstractions
35 Citations2000Yuval Shaḥar, Cleve Cheng
A domain-independent framework specific to the task of interpretation, summerization, visualization, explanation, and interactive navigation in a context-sensitive manner through time-oriented raw data and the multiple levels of higher-level, interval-based concepts that can be abstracted from these data.
Journal of Intelligent Information SystemsDeriving Trends in Historical and Real-Time Continuously Sampled Medical Data
34 Citations1999Apkar Salatian, Jim Hunter
A system which abstracts continuous data into trends is developed which consists of three consecutive processes: filtering which smooths the data; temporal interpolation which creates simple intervals between consecutive data points; and temporal inference which iteratively merges intervals which share similar characteristics into larger intervals.
Modeling customizable Web applications - a requirement's perspective
33 Citations2002Gerti Kappel, Werner Retschitzegger +1 more
A framework of requirements, covering the design space of customize Web applications is suggested and existing approaches for developing customizable Web applications are surveyed and general shortcomings are identified pointing the way to next-generation modeling methods.
Journal of the American Medical Informatics AssociationSemi-automated Entry of Clinical Temporal-abstraction Knowledge
30 Citations1999Yuval Shaḥar, Haofeng Chen +5 more
The authors demonstrate that the KA tool is usable and effective for expert physicians and knowledge engineers to enter clinical temporal-abstraction knowledge and that the resulting knowledge bases are as valid as those produced by manual entry.
A Framework for Visualizing Information
29 Citations2002Ed H.
This work presents a model for evaluating the Expressiveness of Data State Model for Web Analysis Visualization Spreadsheet and describes the implementation experience of this model.
Representation of temporal intervals and relations: information visualization aspects and their evaluation
29 Citations2002Luca Chittaro, Carlo Combi
This paper proposes three new solutions for the visualization of temporal intervals and relations, also evaluating them with a proper user study.
PubMedEvaluation of KNAVE-II: a tool for intelligent query and exploration of patient data.
28 Citations2004Susana B. Martins, Yuval Shaḥar +6 more
Annals of Mathematics and Artificial IntelligenceCAPSUL: A constraint-based specification of repeating patterns in time-oriented data
24 Citations2000Shubha Chakravarty, Yuval Shaḥar
The syntax of CAPSUL is described in detail, including its layers of abstraction and four types of constraints, including the concept of interference between patterns and the expressive power of the language.
Pattern Analysis and ApplicationsKnowledge-based spatiotemporal linear abstraction
21 Citations1998Yuval Shaḥar, Martín Molina
The results suggest that the knowledge-base temporal-abstraction method is reusable over time and unidimensional space as well as over significantly different domains, and the method can be generalised into a knowledge-based linear-abStraction method, which solves tasks requiring abstraction of data along any linear distance measure.
Applying Temporal Abstraction in Medical Information Systems
18 Citations2003Mira Balaban, David Boaz +1 more
The Temporal Abstraction Language (TAR) is introduced, which enablesspecification of abstract relations involving raw data and abstract concepts, and used for typical medicalabstraction patterns.
Journal of Intelligent Information SystemsA Multidimensional and Multigranular Model of Time for Medical Knowledge-Based Systems
17 Citations1999Elpida Keravnou
This paper presents a multidimensional and multigranular model of time for knowledge-based problem solving, primarily for medical applications and discusses at length the two classes of time-axes, namely the atomic axes and the spanning axes.
Methods of Information in MedicineAcquisition and Analysis of Repeating Patterns in Time-oriented Clinical Data
16 Citations2001Shubha Chakravarty, Yuval Shaḥar
The CAPSUL language enables medical experts to express temporal patterns involving multiple levels of abstraction of clinical data and the ability to reuse both domain-patterns and abstract constraints seems highly useful.
Dynamic queries, starfield displays, and the path to Spotfire
14 Citations2005Ben Shneiderman
The old days of command line interfaces and submitting queries to databases are passing quickly and in their place are dynamic queries and starfield displays that update a two-dimensional graphical display in 100 milliseconds.
Time-Oriented Analysis of High-Frequency Data in ICU Monitoring
7 Citations1997Silvia Miksch, Werner Horn +2 more
Analysis methods of high-frequency data to abstract qualitative descriptions over a period of time to arrive at unified qualitative values or patterns, comprehensible to health care providers and easy to use for decision support are presented.
IGI Global eBooksDesigning Model-Based Intelligent Dialogue Systems
7 Citations2001Dina Goren‐Bar
The implementation of the model is shown by describing an application named Stigma-A STereotypical Intelligent General Matching Agent for Improving Search Results on the Internet and the differences and the advantages of the proposed model are compared.
