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Aphanamolide A, a New Limonoid from <i>Aphanamixis polystachya</i>

Organic LettersPublished 6 December 2010
Sheng‐Ping Yang, Huadong Chen, Shang‐Gao Liao, Bojun Xie, Ze‐Hong Miao, Jian‐Min Yue
Citations49
SJR quartileQ1
SJR score1.24
SNIP1.03

TL;DR

Two new limonoids, namely aphanamolides A and B, were isolated from the seeds of Aphanamixis polystachya and featured an unprecedented carbon skeleton via the formation of a C-3-C-6 bond.

Abstract

Two new limonoids, namely aphanamolides A (1) and B (2), were isolated from the seeds of Aphanamixis polystachya . Their structures were established by spectroscopic methods. Aphanamolide A (1) featured an unprecedented carbon skeleton via the formation of a C-3-C-6 bond. Compounds 1 and 2 showed cytotoxic activity against two tumor cell lines.

Keywords

Materials ScienceBiochemistry, Genetics and Molecular Biology