Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients
NaturePublished 1 January 1985
Theodore G. Krontiris, Nancy A. DiMartino, Mark Colb, David Parkinson
Citations283
SJR quartileQ1
SJR score18.29
SNIP10.16
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TL;DR
White blood cell DNA from cancer patients and DNA from tumours and tumour-derived cell lines frequently demonstrated allelic restriction fragments of the Harvey ras oncogene locus not found in the unaffected population, which may be linked to susceptibility to cancer.
Abstract
White blood cell DNA from cancer patients and DNA from tumours and tumour-derived cell lines frequently demonstrated allelic restriction fragments of the Harvey ras oncogene locus not found in the unaffected population. The presence of such unusual alleles may be linked to susceptibility to cancer.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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