Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder
American Journal of PsychiatryPublished 1 December 1993
Kristin S. Cadenhead, Mark A. Geyer, David Braff
Citations308
SJR quartileQ1
SJR score5.27
SNIP3.68
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TL;DR
It is suggested that subjects with schizotypal personality disorder perceive the prepulse stimuli but still demonstrate deficient sensorimotor gating of amplitude, which supports the importance of startle prepulse inhibition and startle habituation as biological markers for schizophrenia spectrum disorders.
Abstract
This pattern of changes in amplitude and latency of the startle response suggests that subjects with schizotypal personality disorder perceive the prepulse stimuli but still demonstrate deficient sensorimotor gating of amplitude. These findings support the importance of startle prepulse inhibition and startle habituation as biological markers for schizophrenia spectrum disorders.
Keywords
PsychologyNeuroscience
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