Protein Sparing Therapy during Periods of Starvation with Sepsis or Trauma
Annals of SurgeryPublished 1 May 1973Open access
CRB Blackburn, J. P. Flatt, G. H. A. Clowes, Thomas F.X. O’Donnell, T. E. HENSLE
Citations223
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Abstract
BLACKBURN, C. L. M.D.; FLATT, J. P. PhD.; CLOWES, G. H. A. JR. M.D.; O'DONNELL, T. F. M.D.; HENSLE, T. E. M.D. Author Information
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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Patients undergoing elective operation in this study did not have a significant rise in RME or nitrogen excretion, and body fat stores are the only other major source of fuel from which the semistarved patient can meet the increased demands for energy.
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It is concluded that mobilization of FFA in obesity is not impaired; on the contrary, it exceeds the energy requirements more than in lean persons.
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The surgeon today is fortunate in that he can take advantage of a great body of experience with this procedure and also can readily employ many useful agents to supply all the necessary requirements.
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The beneficial effect of the essential amino acids on the nitrogen balance and the plasma urea was enhanced by the addition of Histidine and also of both histidine and arginine to the amino acid solution.
