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The Combined Effect of Modern Highly Active Antiretroviral Therapy Regimens and Adherence on Mortality Over Time

JAIDS Journal of Acquired Immune Deficiency SyndromesPublished 1 April 2009
Viviane D. Lima, Richard Harrigan, David R. Bangsberg, Robert S. Hogg, Robert Gross, Benita Yip
Citations315
SJR quartileQ1
SJR score1.04
SNIP0.81

TL;DR

Incomplete adherence to modern HAART over time was strongly associated with increased mortality, and patients on efavirenz-based NNRTI therapies were particularly at a higher risk if nonadherent.

Abstract

Incomplete adherence to modern HAART over time was strongly associated with increased mortality, and patients on efavirenz-based NNRTI therapies were particularly at a higher risk if nonadherent. These results highlight the need to develop further strategies to help sustain high levels of adherence on a long-term basis.

Keywords

Medicine