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Histone acetylation in chromatin structure and transcription

NaturePublished 1 September 1997
Michael Grunstein
Citations2,883
SJR quartileQ1
SJR score18.29
SNIP10.16

TL;DR

The amino termini of histones extend from the nucleosomal core and are modified by acetyltransferases and deacetylases during the cell cycle, which may direct histone assembly and help regulate the unfolding and activity of genes.

Abstract

'The amino termini of histones extend from the nucleosomal core and are modified by acetyltransferases and deacetylases during the cell cycle. These acetylation patterns may direct histone assembly and help regulate the unfolding and activity of genes.

Keywords

Biochemistry, Genetics and Molecular Biology