The Acute Respiratory Distress Syndrome
New England Journal of MedicinePublished 5 January 1995
Marin H. Kollef, Daniel P. Schuster
Citations553
SJR quartileQ1
SJR score19.08
SNIP13.47
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TL;DR
To maintain progress, new therapies for ARDS must be rigorously evaluated, and their routine use should be recommended only after careful scrutiny of the evidence.
Abstract
ARDS is a complex response of the lung to direct (inhalational) and indirect (hematogenous) insults. It is easy to be pessimistic about the benefit of the approaches we have described, but there is evidence that overall survival has improved in recent years. To maintain this progress, new therapies for ARDS must be rigorously evaluated, and their routine use should be recommended only after careful scrutiny of the evidence. Such a course will eliminate the unnecessary risks and costs often associated with unproved therapies.
Keywords
MedicineEngineering
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Clinics in Chest MedicineMechanisms and Mediators of the Adult Respiratory Distress Syndrome
105 Citations1990Jean E. Rinaldo, John W. Christman
The age of the "mediator" of ARDS, and of the corresponding therapeutic "magic bullet," is over, and the complexity of the redundant networks by which inflammation is regulated seems bewildering in relation to ARDS.
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