The replication of DNA in <i>Escherichia coli</i>
Proceedings of the National Academy of SciencesPublished 15 July 1958Open access
Matthew Meselson, Franklin W. Stahl
Citations1,227
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TL;DR
A method was developed for the detection of small density differences among macromolecules and the distribution of the heavy nitrogen isotope N15 among molecules of DNA following the transfer of a uniformly N15-labeled, exponentially growing bacterial population to a growth medium containing the ordinary nitrogen isotopes.
Abstract
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Keywords
Biochemistry, Genetics and Molecular Biology
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