Three-dimensional functional magnetic resonance imaging of human brain on a clinical 1.5-T scanner.
Proceedings of the National Academy of SciencesPublished 18 July 1995Open access
Peter van Gelderen, Nick F. Ramsey, Guoying Liu, J.H. Duyn, Joseph A. Frank, D.R. Weinberger
Citations141
SJR quartileQ1
SJR score3.41
SNIP2.38
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TL;DR
An efficient three-dimensional fMRI method is presented for imaging brain activity on conventional, widely available, 1.5-T scanners, without additional hardware that uses large magnetic susceptibility weighting based on the echo-shifting principle combined with multiple gradient echoes per excitation.
Abstract
Functional magnetic resonance imaging (fMRI) is a tool for mapping brain function that utilizes neuronal activity-induced changes in blood oxygenation. An efficient three-dimensional fMRI method is presented for imaging brain activity on conventional, widely available, 1.5-T scanners, without additional hardware. This approach uses large magnetic susceptibility weighting based on the echo-shifting principle combined with multiple gradient echoes per excitation. Motor stimulation, induced by self-paced finger tapping, reliably produced significant signal increase in the hand region of the contralateral primary motor cortex in every subject tested.
Keywords
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