login

RNA silencing: small RNAs as ubiquitous regulators of gene expression

Current Opinion in Plant BiologyPublished 1 October 2002
Olivier Voinnet
Citations150
SJR quartileQ1
SJR score3.19
SNIP1.79

TL;DR

Initially identified as an immune system that is targeted against transposons and viruses, RNA silencing is emerging as a fundamental regulatory process that is likely to affect many layers of endogenous gene expression in most, if not all, eukaryotes.

Abstract

'RNA silencing' is the suppression of gene expression through nucleotide sequence-specific interactions that are mediated by RNA. Initially identified as an immune system that is targeted against transposons and viruses, RNA silencing is emerging as a fundamental regulatory process that is likely to affect many layers of endogenous gene expression in most, if not all, eukaryotes.

Keywords

Agricultural and Biological SciencesBiochemistry, Genetics and Molecular Biology