Global cocaine intoxication research trends during 1975–2015: a bibliometric analysis of Web of Science publications
Substance Abuse Treatment Prevention and PolicyPublished 2 February 2017Open access
Sa’ed H. Zyoud, W. Stephen Waring, Samah W. Al‐Jabi, Waleed M. Sweileh
Citations112
SJR quartileQ1
SJR score1.25
SNIP1.25
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
This is the first bibliometric approach to examining research related to cocaine toxicity and shows that research activity has become more global and extensive since 1990.
Abstract
This is the first bibliometric approach to examining research related to cocaine toxicity and shows that research activity has become more global and extensive since 1990. The USA remains the leading country regarding published literature, the highest h-index, and greatest role in international collaborations.
Keywords
PsychologyBiochemistry, Genetics and Molecular BiologyPharmacology, Toxicology and Pharmaceutics
ScientometricsSoftware survey: VOSviewer, a computer program for bibliometric mapping
19,836 Citations2009Nees Jan van Eck, Ludo Waltman
VOSviewer’s ability to handle large maps is demonstrated by using the program to construct and display a co-citation map of 5,000 major scientific journals.
The FASEB JournalComparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses
4,818 Citations2007Matthew E. Falagas, Eleni Pitsouni +2 more
The content coverage and practical utility of PubMed, Scopus, Web of Science, and Google Scholar are compared and PubMed remains an optimal tool in biomedical electronic research.
NatureBibliometrics: The Leiden Manifesto for research metrics
2,643 Citations2015Diana Hicks, Paul Wouters +3 more
Annual Review of Information Science and TechnologyScholarly communication and bibliometrics
1,124 Citations2002Christine L. Borgman, Jonathan Furner
The Future of Bibliometrics and its Applications: A Case Study of Agricultural Research Within the European Community Core Journals of the Rapidly Changing Research Front of "Superconductivity" is reviewed.
Proceedings of the National Academy of SciencesActivation of memory circuits during cue-elicited cocaine craving.
947 Citations1996Stephanie Grant, Edythe D. London +7 more
Correlations of metabolic increases in the dorsolateral prefrontal cortex, medial temporal lobe, and cerebellum with self-reports of craving suggest that a distributed neural network, which integrates emotional and cognitive aspects of memory, links environmental cues with cocaine craving.
Proceedings of the National Academy of SciencesAntidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.
887 Citations1993Sammanda Ramamoorthy, Andrea L. Bauman +6 more
A Na(+)- and Cl(-)-coupled serotonin (5-hydroxytryptamine, 5HT) transporter is expressed on human neuronal, platelet, placental, and pulmonary membranes and sequence analysis reveals a 630-amino acid open reading frame bearing 92% identity to the cloned rat brain 5HT transporter.
Clinical Toxicology2013 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 31st Annual Report
840 Citations2014James B. Mowry, Daniel A. Spyker +3 more
These data support the continued value of PC expertise and need for specialized medical toxicology information to manage the more severe exposures, despite a decrease in calls involving less severe exposures.
JAMAComparisons of Citations in Web of Science, Scopus, and Google Scholar for Articles Published in General Medical Journals
806 Citations2009Abhaya V. Kulkarni
Comparing the citation count profiles of articles published in general medical journals among the citation databases of Web of Science, Scopus, and Google Scholar produced quantitatively and qualitatively different citation counts.
PLoS ONEIntense Sweetness Surpasses Cocaine Reward
579 Citations2007Magalie Lenoir, Fuschia Serre +2 more
It is clearly demonstrate that intense sweetness can surpass cocaine reward, even in drug-sensitized and -addicted individuals.
Journal of NeuroscienceLimbic and Motor Circuitry Underlying Footshock-Induced Reinstatement of Cocaine-Seeking Behavior
526 Citations2004Krista McFarland, Susan B. Davidge +2 more
The role of limbic, cortical, and striatal circuitry in a footshock reinstatement model of relapse to cocaine seeking was evaluated and suggested that footshock activates limbic circuitry in the CEA, which in turn activates a VTA dopamine projection to the PFCd.
Clinical Toxicology2014 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 32nd Annual Report
497 Citations2015James B. Mowry, Daniel A. Spyker +3 more
These data support the continued value of PC expertise and need for specialized medical toxicology information to manage moreserious exposures, despite a decrease in calls involving less serious exposures, as well as support the near real-time, always current status of NPDS.
Nature NeuroscienceDifferential control over cocaine-seeking behavior by nucleus accumbens core and shell
491 Citations2004Rutsuko Ito, Trevor W. Robbins +1 more
A neural double-dissociation of the behavioral processes that underlie cocaine self-administration in rats is shown, further understanding of how the NAc controls drug-seeking and drug-taking behavior.
Pharmacotherapy The Journal of Human Pharmacology and Drug TherapyA Descriptive and Historical Review of Bibliometrics with Applications to Medical Sciences
469 Citations2015Dennis F. Thompson, Cheri K. Walker
Bibliometrics has considerable potential as a research area for health care scientists and practitioners that can be used to discover new information about academic trends, pharmacotherapy, disease, and broader health sciences trends.
PubMedExcitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement.
305 Citations1996Rachel B. Whitelaw, Athina Markou +2 more
Drug Testing and AnalysisAdulterants in illicit drugs: a review of empirical evidence
283 Citations2010Claire Cole, Lisa Jones +4 more
From the reports gathered, adulterants are predominantly substances which are readily available, commonly being caffeine, procaine, paracetamol, and sugars, which are likely to have minimal impact on users' health at low dosages.
Journal of the Medical Library Association JMLABibliometric indicators: opportunities and limits
281 Citations2015Chris Belter
Although the use of bibliometric indicators can provide a valuable supplement to the peer-review process, these indicators are all too often taken out of context and applied without a full understanding of the bibliometrics research on which they are based.
Journal of NeuroscienceDopamine D<sub>3</sub>Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in Rats
268 Citations2002Stanislav R. Vorel, Charles R. Ashby +7 more
An important role for D3 receptors in mediating the addictive properties of cocaine is suggested and blockade of dopamine D3receptors may constitute a new and useful target for prospective pharmacotherapies for cocaine addiction.
JAMAToxicity Associated With Long-term Intravenous Heroin and Cocaine Self-administration in the Rat
260 Citations1985Michael A. Bozarth
It is suggested that cocaine is a much more toxic compound than heroin when animals are given unlimited access to intravenous drug.
The Use of Bibliometrics for Assessing Research: Possibilities, Limitations and Adverse Effects
251 Citations2014Stefanie Haustein, Vincent Larivière
This chapter provides an overview of bibliometric methods, from the development of citation indexing as a tool for information retrieval to its application in research evaluation, and discusses their misuse and effects on researchers’ scholarly communication behavior.
PsychopharmacologyExcitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement
228 Citations1996Rachel B. Whitelaw, Athina Markou +2 more
A dissociation in the neural mechanisims underlying cocaine-taking and cocaine seeking behaviour is suggested, and the potential importance of the basolateral amygdala is demonstrated in the processes by which previously neutral stimuli gain control over drug-seeking behaviour.
ScientometricsMajor trends in knowledge management research: a bibliometric study
215 Citations2016Peyman Akhavan, Nader Ale Ebrahim +2 more
This study provides an overview of the knowledge management literature from 1980 through 2014 by employing bibliometric and text mining analyses on a sample of 500 most cited articles to examine the impact of factors such as number of authors, references, pages, and keywords on the number of citations that they received.
CHEST JournalAsystole and Ventricular Fibrillation Associated with Cocaine Intoxication
211 Citations1984Amin A. Nanji, J. Douglas Filipenko
A patient with cocaine intoxication in whom the initial presentation was that of asystole and ventricular fibrillation is discussed, suggesting cocaine intoxication should be considered in any patient with unexplained cardiac arrest or ventricular arrhythmias.
Journal of Pharmacology and Experimental TherapeuticsAlcohol and cocaine interactions in humans.
200 Citations1993Magı́ Farré, Rafael de la Torre +5 more
The combination of COC and alcohol induced a nonsignificant decrease in the subjective feelings of drunkeness, an increase in COC-induced euphoria, a significant improvement in alcohol-related changes in psychomotor performance and a marked increase in heart rate.
PLoS ONEBibliometric Evidence for a Hierarchy of the Sciences
193 Citations2013Daniele Fanelli, Wolfgang Glänzel
A “gradualist” view of scientific knowledge is suggested, suggesting that the Hierarchy of the Sciences provides the best rational framework to understand disciplines' diversity, by sampling nearly 29,000 papers published contemporaneously in 12 disciplines and measuring a set of parameters hypothesised to reflect theoretical and methodological consensus.
CirculationCocaine Increases the Endothelial Release of Immunoreactive Endothelin and Its Concentrations in Human Plasma and Urine
179 Citations1998Ute Wilbert-Lampen, Christian Seliger +2 more
It is suggested that cocaine increases the endothelin-1 release in vitro and in vivo and may prove to play a role in vasospastic angina, acute myocardial infarction, and sudden cardiac death.
Reproductive ToxicologyFetal effects of cocaine: an updated meta-analysis
177 Citations2001Antonio Addis, Myla E. Moretti +3 more
Many of the perinatal adverse effects commonly attributed to cocaine may be caused by the multiple confounders that can occur in a cocaine using mother.
Neuroscience & Biobehavioral ReviewsSigma1 (σ1) receptor antagonists represent a new strategy against cocaine addiction and toxicity
151 Citations2002Tangui Maurice, Rémi Martin‐Fardon +2 more
The present review will bring concise overviews of the present strategies followed to alleviate cocaine addiction and animal models developed to analyze the pharmacology of cocaine addiction, and evidence involving activation of the sigma(1) receptor in the different aspects of cocaine abuse, will be detailed, following acute, repeated, or overdose administration.
Heart Failure ReviewsPathophysiological mechanisms of catecholamine and cocaine-mediated cardiotoxicity
147 Citations2014Lucas Liaudet, Belinda Calderari +1 more
The aim of the current review is to present in detail the pathophysiological processes underlying the development of catecholamine and cocaine-induced cardiomyopathy, as such conditions may be frequently encountered in the clinical practice of cardiologists and ICU specialists.
Therapeutic Drug MonitoringToxicokinetics of Drugs of Abuse: Current Knowledge of the Isoenzymes Involved in the Human Metabolism of Tetrahydrocannabinol, Cocaine, Heroin, Morphine, and Codeine
147 Citations2006Hans H. Maurer, Christoph Sauer +1 more
The detection times of these drugs and/or their metabolites in biological samples are summarized and the implications of the presented data on the possible interactions of drugs of abuse with other xenobiotics, ie, inhibition or induction of individual polymorphic and nonpolymorphic isoenzymes, discussed.
Critical Care ClinicsCocaine Intoxication
138 Citations2012Janice L. Zimmerman
Cocaine, a natural alkaloid derived from the coca plant, is one of the most commonly abused illicit drugs and the clinical presentation may primarily result from organ toxicity.
Journal of Pharmacology and Experimental TherapeuticsCocaine and Alcohol Interactions in Humans: Neuroendocrine Effects and Cocaethylene Metabolism
138 Citations1997Magı́ Farré, Rafael de la Torre +5 more
The combination of alcohol and cocaine produced greater increases in HR, rate-pressure product and pleasurable-related subjective effects (euphoria, well-being) compared with the effects of cocaine, and the augmented subjective euphoria may explain why the drug combination is more likely to be abused than is cocaine or alcohol alone.
American Journal of Cardiovascular DrugsCocaine Cardiotoxicity
132 Citations2009Katharine R.B. Phillips, Adriana Luk +4 more
Clinicians should be suspicious of cocaine use in their differential diagnosis of chest pain, especially in the younger male population, and proceed more cautiously when use is suspected, because of documented adverse effects.
Molecular PharmacologyNeuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6.
126 Citations1991Rachel F. Tyndale, Roger K. Sunahara +4 more
Data indicate that P450IID1 is expressed centrally and is similar, at the functional and molecular levels, to the human hepatic P450 IID1 enzyme, which may possibly lead to differences in drug response and toxicity.
Journal of ElectrocardiologyAborted sudden death, transient Brugada pattern, and wide QRS dysrrhythmias after massive cocaine ingestion
122 Citations2001J. Ortega-Carnicer, Juan Bertos-Polo +1 more
A patient with massive cocaine ingestion who developed psychomotor agitation and generalized seizures followed by asystolic cardiac arrest is reported, and the electrocardiogram showed accelerated junctional rhythm at 85 beats/min resembling the Brugada syndrome.
Journal of Nanoparticle ResearchNanotechnology publications and citations by leading countries and blocs
118 Citations2008Jan Youtie, Philip Shapira +1 more
PubMedCocaine cardiotoxicity: a review of the pathophysiology, pathology, and treatment options.
118 Citations2009Katharine R.B. Phillips, Adriana Luk +4 more
Clinicians should be suspicious of cocaine use in their differential diagnosis of chest pain, especially in the younger male population, and proceed more cautiously when use is suspected, because of documented adverse effects.
Clinical ToxicologyTreatment of cocaine cardiovascular toxicity: a systematic review
106 Citations2016John R. Richards, D Garber +7 more
High-quality evidence for pharmacological treatment of cocaine cardiovascular toxicity is limited but can guide acute management of associated tachycardia, dysrhythmia, hypertension, and coronary vasospasm in cocaine-toxic patients.
European Journal of AgronomyBibliometric analysis of research activity in the “Agronomy” category from the Web of Science, 1997–2011
102 Citations2013Ignacio Cañas Guerrero, Fernando R. Mazarrón +3 more
Current Medicinal ChemistryData Available on the Extent of Cocaine Use and Dependence: Biochemistry, Pharmacologic Effects and Global Burden of Disease of Cocaine Abusers
100 Citations2012Cristoforo Pomara, Tommaso Cassano +5 more
The effects of Cocaine mainly depend on the user's addiction, the dose received and the mode of assumption, so ascribing adverse health effect to a certain drug might be difficult.
Trends in Cardiovascular MedicineCardiovascular consequences of cocaine use
96 Citations2014Rachel V. Stankowski, Robert A. Kloner +1 more
The most up-to-date literature regarding the mechanisms of cocaine-associated cardiotoxicity and clinical consequences, diagnosis, and treatment are discussed; relevant controversies are discussed while proposing several important areas for future research.
Archives of ToxicologyBiomechanisms of cocaine-induced hepatocyte injury mediated by the formation of reactive metabolites
94 Citations1991Urs A. Boelsterli, Christian Göldlin
The rodent model of cocaine hepatotoxicity is commensurate with the concept that a multistep, mainly cytochrome P-450 dependentN-oxidative pathway is responsible for the expression of hepatocellular injury, and glutathione plays a pivotal protective role against cocaine-induced hepatic injury.
Brain ResearchProtein kinases A and C are involved in the mechanisms underlying consolidation of cocaine place conditioning
93 Citations1997Luigi Cervo, S Mukherjee +2 more
Changes in the activity of PKA and PKC may be part of the cascade of events that contribute to enhancing synaptic responses in the consolidation phase of cocaine CPP and determine rats' behavior associated with the memory of the rewarding effect of cocaine during cocaine C PP expression.
Journal of Emergency MedicineMedical outcome of cocaine bodystuffers
93 Citations2000Robert June, Steven E. Aks +2 more
A descriptive retrospective analysis was performed on all cases of cocaine bodystuffers received by a metropolitan poison control center and associated toxicology service from January 1993 to May 1994, identifying 46 cases of patients classified as bodystuffer.
Human & Experimental ToxicologyWorldwide research productivity of paracetamol (acetaminophen) poisoning
91 Citations2014Sa’ed H. Zyoud, Samah W. Al‐Jabi +1 more
Evidence is demonstrated that research productivity related to paracetamol poisoning has increased rapidly during the recent years, and certain smaller country such as Nigeria has high scientific output relative to their population size and GDP.
Journal of Chromatography ACapillary electrophoresis for the investigation of illicit drugs in hair: determination of cocaine and morphine
90 Citations1993Franco Tagliaro, Claudio Poiesi +4 more
Capillary electrophoresis was first used for the determination of illicit drugs, such as cocaine and morphine, in the hair of heroin and cocaine users, using 100-mg samples.
European Journal of Pharmacology Environmental Toxicology and PharmacologyCocaine N-demethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors
90 Citations1994Pertti Pellinen, Paavo Honkakoski +6 more
It is suggested that CYP3A plays a prominent role in the N-demethylation of cocaine for the following reasons: (i) pregnenolone-16 alpha-carbonitrile, an inducer of CyP3As increases cocaine N- Demethylase in parallel with testosterone 6 beta-hydroxylase activity and immunoreactive 3A protein in mouse liver.
Emergency Medicine JournalPackers, pushers and stuffers--managing patients with concealed drugs in UK emergency departments: a clinical and medicolegal review
88 Citations2009R J Booker, Jason Smith +1 more
The evidence behind the clinical management of patients involved in body packing, pushing and stuffing and the legal powers afforded to the authorities to authorise the use of intimate searches and diagnostic imaging for forensic purposes are examined.
SpringerPlusBibliometric profile of the global scientific research on autism spectrum disorders
83 Citations2016Waleed M. Sweileh, Samah W. Al‐Jabi +2 more
There is a worldwide growth of publications on ASD led by countries in Northern America and Europe, and molecular genetics of ASD is the primary hot topic on ASD.
Clinical ToxicologyManagement of cocaine-induced cardiac arrhythmias due to cardiac ion channel dysfunction
81 Citations2009David M. Wood, Paul I. Dargan +1 more
The animal and human evidence for ion channel dysfunction is reviewed, and the effects of catecholamines are followed from the cardiac action potential to the development of arrhythmias, to develop a rational treatment strategy for patients with cocaine-induced cardiac arrh rhythmias.
Telematics and InformaticsHall of fame for mobile commerce and its applications: A bibliometric evaluation of a decade and a half (2000–2015)
79 Citations2016Jun-Jie Hew
This study serves as a forerunner in using bibliometric analysis to evaluate researches on mobile commerce and its applications, and is expected to benefit researchers in the area of mobile commerce, by identifying potential research directions.
Archives of ToxicologyHair analysis for drugs of abuse
76 Citations1992Yuji Nakahara, Toshiaki Ochiai +1 more
The results suggest that the incorporation of drugs into hair from blood unexpectedly depends upon the physical properties of each drug.
El Profesional de la InformacionBibliometric methods for detecting and analysing emerging research topics
74 Citations2012Wolfgang Glänzel
This study gives an overview of the process of clustering scientific disciplines using hybrid methods, detecting and labelling emerging topics and analysing the results using bibliometrics methods.
Neurotoxicity ResearchA Comprehensive View of the Neurotoxicity Mechanisms of Cocaine and Ethanol
73 Citations2015Renato B. Pereira, Paula B. Andrade +1 more
A global perspective is provided about the mechanisms of the neurotoxicity of cocaine and ethanol to provide a global perspective about the mechanism by which they damage the nervous tissue.
Clinical Obstetrics & GynecologyThe Maternal, Fetal, and Neonatal Effects of Cocaine Exposure in Pregnancy
71 Citations2013Mary Ashley Cain, P. W. Bornick +1 more
The pregnancy-specific maternal, fetal, and neonatal risks of cocaine use during the antepartum period are reviewed.
ScientometricsLatin American scientific output in Public Health: combined analysis using bibliometric, socioeconomic and health indicators
70 Citations2014Zaida Chinchilla‐Rodríguez, Grisel Zacca-González +2 more
The main results reveal that the research systems with the greatest capacity to communicate scientific results are those of Brazil and Mexico, and potentially Colombia and Argentina, while Uruguay, Puerto Rico and Peru, countries with high rates of collaboration, have the best visibility.
Molecular BrainCocaine induces cell death and activates the transcription nuclear factor kappa-b in pc12 cells
69 Citations2009Lucília Brochado Lepsch, Carolina Demarchi Munhoz +8 more
The results suggest that cocaine induces cell death (apoptosis and necrosis) and activates NF-κB in PC12 cells and seems to have an anti-apoptotic effect on these cells.
HepatologyOxygen free radical production mediated by cocaine and its ethanol-derived metabolite, cocaethylene, in rat hepatocytes
65 Citations1993Urs A. Boelsterli, Armin Wolf +1 more
The data suggest that reactive oxygen species, generated during the interaction of cocaine and cocaethylene with cytochrome P‐450, may be the common mediators of hepatotoxicity induced by these compounds.
Journal of the Royal Society of MedicineCocaine: History, Use, Abuse
60 Citations1999Steven B. Karch
The net effect of technical advances in the cocaine trade has been to increase the amount of cocaine that users of this drug can get into their bodies.
European Journal of NeuroscienceDistribution of α‐ and γ‐synucleins in the adult rat brain and their modification by high‐dose cocaine treatment
59 Citations2003Maria S. Brenz Verca, Amine Bahí +3 more
In a screening for genes differentially expressed after high‐dose cocaine exposure, γ‐synuclein was found as a major upregulated candidate in the tegmentum, and the role of synucleins in relation to cocaine‐induced plasticity or neurotoxicity is discussed.
BMJ OpenEvolution of primary care databases in UK: a scientometric analysis of research output
57 Citations2016Paraskevas Vezyridis, Stephen Timmons
The UK has been well placed at the centre of an expanding global scientific community, facilitating international collaborations and bringing together international expertise in medicine, biochemical and pharmaceutical research.
ScientometricsMapping the scientific research in organic farming: a bibliometric review
56 Citations2015José Luis Aleixandre, José Luis Aleixandre-Tudó +2 more
European Journal of PharmacologyCocaine-induced liver injury in mice is mediated by nitric oxide and reactive oxygen species
55 Citations1997Kimiko Aoki, Mitsuyo Ohmori +3 more
Findings suggest that a hydroxyl radical produced by the reaction of NO and superoxide anion (O2-) via peroxynitrite may be involved in the pathogenesis of cocaine hepatotoxicity.
Drug Metabolism and DispositionIdentification of cytochrome P-450IIB1 as a cocaine-bioactivating isoform in rat hepatic microsomes and in cultured rat hepatocytes.
55 Citations1992Urs A. Boelsterli, A Lanzotti +2 more
It is suggested that cocaine is metabolized and bioactivated by P-450IIB1 in the rat liver, and that induction of this isoform with various agents may be associated with enhanced lethal hepatocyte injury in the rats.
European Journal of Gastroenterology & HepatologyGlobal trends in Helicobacter pylori research from 1991 to 2008 analyzed with the Science Citation Index Expanded
54 Citations2011Fat‐Moon Suk, Gi‐Shih Lien +2 more
It can be concluded that application of H. pylori in clinical gastroenterology, especially research related to ‘cancer’ is the orientation of all the H.pylori research in the 21st Century.
Globalization and HealthA bibliometric analysis of literature on malaria vector resistance: (1996 – 2015)
53 Citations2016Waleed M. Sweileh, Ansam F. Sawalha +4 more
Publications on insecticide resistance in malaria vector has gained momentum in the past decade and international collaborations enhanced the knowledge about the situation of vector resistance in countries with endemic malaria.
Journal of Diabetes & Metabolic DisordersScientometric study of academic publications on antioxidative herbal medicines in type 2 diabetes mellitus
52 Citations2016Ozra Tabatabaei‐Malazy, A. H. Ramezani +3 more
This study provided practical information to researchers who look for studies with potentially highly citation, and also would be helpful for researchers to conduct better researches that eventually could lead to more publications in this field.
PubMedA bibliometric analysis of publications on pluripotent stem cell research.
51 Citations2015Changshuan L. Lin, Yuh‐Shan Ho
A comprehensive analysis of highly cited articles in the stem cell field could identify milestones and important contributors, giving a historic perspective on scientific progress.
Journal of Occupational Medicine and ToxicologyBibliometric profile of the global scientific research on methanol poisoning (1902–2012)
47 Citations2015Sa’ed H. Zyoud, Samah W. Al‐Jabi +3 more
PubMedHair analysis for drugs of abuse. VII. The incorporation rates of cocaine, benzoylecgonine and ecgonine methyl ester into rat hair and hydrolysis of cocaine in rat hair.
46 Citations1994Yuji Nakahara, Ruri Kikura
Human & Experimental ToxicologyScientific research related to calcium channel blockers poisoning
45 Citations2015Sa’ed H. Zyoud, Samah W. Al‐Jabi +2 more
Examining the publication pattern related to CCBs poisoning at the global level using bibliometric analysis of articles published in SciVerse Scopus online database found the amount of CCBs-based research activity was low or not available in most countries.
Journal of Analytical ToxicologyAnalysis of Cocaine and Its Metabolites from Biological Specimens Using Solid-Phase Extraction and Positive Ion Chemical Ionization Mass Spectrometry
44 Citations1995Dennis J. Crouch, M. E. Alburges +4 more
An accurate and reliable gas chromatographic-mass spectrometric method was developed to analyze tissue, whole blood, plasma, and urine samples for cocaine and its major metabolites and was used to quantitate cocaethylene and to identify norcocaine.
Archives of ToxicologyHair analysis for drugs of abuse
42 Citations1994Yuji Nakahara, Ruri Kikura
It was concluded that the incorporation rates of BE and EME into hair were very low in comparison with that of cocaine and most of the BE detected in hair would be a hydrolytic product derived from cocaine in hair matrix after incorporation.
AlcoholIncreased stimulatory effect by the combined administration of cocaine and alcohol in mice
41 Citations1989Jandira Masur, Maria Lúcia Oliveira de Souza Formigoni +1 more
The increase in locomotion induced by the association of cocaine plus ethanol was significantly larger when compared to either the group injected with only cocaine or only ethanol.
Expert Review of Clinical PharmacologyIntravenous lipid administration for drug-induced toxicity: a critical review of the existing data
40 Citations2012W. Stephen Waring
Too few data exist to adequately address the safety profile of ILE, and a number of different mechanisms are proposed, from preferential partitioning of the drug from cardiac tissue to the circulating lipid fraction and direct inotropic effects related to carnitine pathways and fatty acid oxidative metabolism.
ScientometricsA bibliometric analysis on the performance and underlying dynamic patterns of water security research
40 Citations2016Cuiqian Huai, Lihe Chai
The findings drawn from a suite of bibliometric indicators are instructive for the future studies of researchers, the strategy/policy of countries and the efforts of publishing organizations, altogether prompting the global water security research.
Journal of Medical ToxicologyJournal impact factors,h indices, and citation analyses in toxicology
36 Citations2008Steven B. Bird
The toxicology journals in which many people in the fields of medical and clinical toxicology publish will see decreased submissions, as authors attempt to get their work published in journals with higher impact factors.
The American Journal of the Medical SciencesCutaneous Vasculopathy and Neutropenia Associated With Levamisole-Adulterated Cocaine
36 Citations2012Natasha Purai Arora
Levamisole-induced cutaneous vasculopathy in cocaine users is characterized by a female predominance, a retiform purpuric rash with a predilection for lower extremities, autoantibody production, leukopenia and/or neutropenia and recurrences with future cocaine use.
MedicineTrends of triple negative breast cancer research (2007–2015)
34 Citations2016Yiran Wang, Xiao Zhai +3 more
Literature growth related to TNBC is expanding rapidly in recent years and the quality of the articles from China still requires improvement, but Narod SA, Gonzalez-Angulo AM, and Hortobagyi GN may be good candidates for collaborative research in this field.
SpringerPlusBibliometric analysis of medicine-related publications on poverty (2005–2015)
33 Citations2016Waleed M. Sweileh, Samah W. Al‐Jabi +3 more
Data indicated that articles on poverty were published in high influential medical journals indicative of the importance of poverty as a global health problem, however, the number publications and the extent of international collaborations was lower than expected given the huge burden of poverty-related health problems.
Human & Experimental ToxicologyGlobal research productivity of <i>N</i> -acetylcysteine use in paracetamol overdose
32 Citations2015Sa’ed H. Zyoud, Samah W. Al‐Jabi +3 more
It is demonstrated that NAC use for paracetamol overdose remains a hot issue in scientific research and may have a larger audience compared with other toxicological aspects and editors and authors in the field of toxicology might usefully promote the submission of work on NAC in future.
BMC Public HealthParticulate matter and atherosclerosis: a bibliometric analysis of original research articles published in 1973–2014
30 Citations2016Feifei Wang, Xiaofeng Jia +3 more
The aorta and endothelium vascular were the principal locations of atherosclerotic lesions, which were enhanced by PM exposure, and Oxidative stress and inflammation were of special concern in the current mechanistic research system.
British Journal of PharmacologyLocal anaesthetic actions of cocaine: effects on excitatory and inhibitory synaptic responses in the hippocampus <i>in vitro</i>
30 Citations1988Thomas V. Dunwiddie, William R. Proctor +1 more
The results suggest that cocaine does not have a selective depressant effect upon inhibitory pathways in the CA1 region of the hippocampus, and although the hippocampus shows epileptiform activity following systemic administration of local anaesthetics such as cocaine in the intact rat, this effect may not reflect a direct hippocampal site of drug action.
Substance Abuse Treatment Prevention and PolicyCocaine treatment admissions at three sentinel sites in South Africa (1997–2006): findings and implications for policy, practice and research
28 Citations2007Charles Parry, Andreas Plüddemann +1 more
Journal of Traumatic StressThe increasing internationalization of mainstream posttraumatic stress disorder research: A bibliometric study
28 Citations2007Ivan Figueira, Mariana da Luz +4 more
Although the number of countries publishing on PTSD has steadily increased, research is still dominated qualitatively and quantitatively by developed countries and the immaturity of PTSD research is demonstrated by the concentration of publications in a few countries.
Multiple Sclerosis JournalBibliometric profile of the global scientific research on multiple sclerosis (2003–2012)
28 Citations2014Rafael Aleixandre‐Benavent, Adolfo Alonso‐Arroyo +4 more
The progressive growth of publications worldwide, the publication of articles in a wide variety of journals covering numerous subject areas, and the research leadership of Western countries, most notably European countries, the US and Canada are emphasised.
Basic & Clinical Pharmacology & ToxicologyIntravenous Lipid Emulsion as an Antidote for the Treatment of Acute Poisoning: A Bibliometric Analysis of Human and Animal Studies
28 Citations2016Sa’ed H. Zyoud, W. Stephen Waring +4 more
Substance Abuse Treatment Prevention and PolicyCocaine and thrombosis: a narrative systematic review of clinical and in-vivo studies
25 Citations2007Nat Wright, M F Martin +4 more
SpringerPlusThe 100 most influential publications in paracetamol poisoning treatment: a bibliometric analysis of human studies
21 Citations2016Sa’ed H. Zyoud, W. Stephen Waring +3 more
This study is the first bibliometric assessment of the top 100 cited articles in toxicology literature and finds research published in high-impact journals and from high income countries is most likely to be cited in published paracetamol research.
Irrigation and DrainageBibliometric Analysis of Research on Wastewater Irrigation During 1991-2014
18 Citations2016Sebastian Maassen
Cardiology in ReviewCurrent Strategies in the Evaluation and Management of Cocaine-Induced Chest Pain
16 Citations2015Pratik R Agrawal, Tiziano M. Scarabelli +6 more
The purpose of this review is to summarize the understanding of cocaine’s cardiovascular pathophysiology and to examine the current approach for proper evaluation and management of CCP.
Expert Review of Cardiovascular TherapyElectrocardiographic findings associated with cocaine use in humans: a systematic review
16 Citations2011F. Daniel Ramirez, Francisco Femenía +4 more
This article sought to systematically review the medical literature to identify the electrocardiographic findings that have been linked to cocaine use in humans in an effort to highlight what physicians can expect to encounter when managing patients using the drug.
Journal of Emergency NursingThe Risky Business of Body Packers and Body Stuffers
16 Citations2006Sheila Goertemoeller, Alysha Behrman
This booklet contains information on how to identify and identify the warning signs of poison oak in the home, as well as simple and effective ways to identify these signs in the clinic.
Pharmacotherapy The Journal of Human Pharmacology and Drug TherapyControversial Therapeutics: The β‐Adrenergic Antagonist and Cocaine‐Associated Cardiovascular Complications Dilemma
16 Citations2014James W. Schurr, Brenda Gitman +1 more
Although case reports support a detrimental effect of β‐adrenergic antagonists, the anecdotal data are inconsistent, and the conclusions from case studies are overruled by larger studies, indicating that future studies that focus on outcomes and different pharmacologic profiles ofβ‐adRenergic antagonists are needed.
Bratislavské lekárske listy/Bratislava medical journalKnowledge mapping analysis of Ebola research
14 Citations2015Xiangna Zhao, Sheng Liu +4 more
The overall situation of research on Ebola virus is revealed via visual knowledge mapping analyses of the literatures regarding Ebola virus all around the world, e.g., literature metrology and topic evolvement through knowledge graph built by comprehensively utilizing software.
ScientometricsThe financial crisis research: a bibliometric analysis
13 Citations2015Chien-Lung Hsu, Chun-Hao Chiang
Clinical Medicine Insights PathologySudden Cardiac Death of a Body Packer Due to Cocaine Cardiotoxicity
13 Citations2016Parthasarathi Pramanik, Raghvendra Kumar Vidua
The detailed autopsy examination, including histopathology and toxicology findings, is discussed with the aim of describing the mechanism of cocaine intoxication in the body packer and an analysis of cocaine-induced cardiotoxicity and sudden death.
ScientometricsA bibliometric analysis of lab-on-a-chip research from 2001 to 2013
9 Citations2015Mohammadmahdi Vakilian, Burhanuddin Yeop Majlis +1 more
The miniaturized analytical device or ‘lab-on-a-chip’ (LOC) has been the subject of increasing interest over the past two decades, especially in the fields of chemical analysis and biological analysis, which has resulted in an increase in the quality and number of published papers related to this topic.
Acute Medicine JournalAn Unusual Complication of Cocaine Toxicity
4 Citations2013Lucy Houghton, Quentin Jones +1 more
The patient was diagnosed with cocaine-induced methaemoglobinaemia and given methyl thioninium chloride (methylene blue) and made an uneventful recovery.
…
