Changes in health in England, with analysis by English regions and areas of deprivation, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
The LancetPublished 14 September 2015Open access
John Newton, Adam Briggs, Christopher J L Murray, Daniel Dicker, Kyle J Foreman, Haidong Wang
Citations353
SJR quartileQ1
SJR score12.11
SNIP22.72
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
The gap in mortality rates between men and women has reduced, but marked health inequalities between the least deprived and most deprived areas remain, and England ranked better than the UK and the EU15+ means.
Abstract
Bill & Melinda Gates Foundation and Public Health England.
Keywords
Social SciencesHealth Professions
The LancetGlobal and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
14,264 Citations2012Rafael Lozano, Mohsen Naghavi +189 more
The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
The LancetDisability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
9,004 Citations2012Christopher J L Murray, Theo Vos +360 more
The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account.
The LancetYears lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
8,388 Citations2012Theo Vos, Abraham D Flaxman +356 more
Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.
The LancetGlobal, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
7,796 Citations2016Mohammad H. Forouzanfar, Ashkan Afshin +652 more
The comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study 2015 was used to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational risks or clusters of risks from 1990 to 2015.
The LancetGlobal, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
7,467 Citations2014Gbd Mortality And Causes of Death Collaborators
The LancetGlobal, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
6,508 Citations2015Theo Vos, Ryan M Barber +677 more
The results can guide future health initiatives through examination of epidemiological trends and a better understanding of variation across countries.
Journal of Health and Social BehaviorSocial Conditions As Fundamental Causes of Disease
5,601 Citations1995Bruce G. Link, Jo C. Phelan
Alzheimer s & DementiaThe global prevalence of dementia: A systematic review and metaanalysis
4,915 Citations2013Martin Prince, Renata Bryce +4 more
A reappraisal of global prevalence and numbers is due, given the significant implications for social and public policy and planning.
The LancetGlobal, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
2,747 Citations2015Mohammad H. Forouzanfar, Lily Alexander +719 more
The Global Burden of Disease, Injuries, and Risk Factor study 2013 is the first of a series of annual updates of the GBD and six new risk factors have been added: handwashing practices, occupational exposure to trichloroethylene, childhood wasting, childhood stunting, unsafe sex, and low glomerular filtration rate.
PubMedSocial Conditions as Fundamental Causes of Disease
2,692 Citations1995Bruce G. Link, Jo C. Phelan
It is argued that social factors such as socioeconomic status and social support are likely "fundamental causes" of disease that, because they embody access to important resources, affect multiple disease outcomes through multiple mechanisms, and consequently maintain an association with disease even when intervening mechanisms change.
GastroenterologyPrimary liver cancer: Worldwide incidence and trends
2,498 Citations2004F. Xavier Bosch, Josepa Ribes +2 more
The incidence of primary liver cancer is increasing in several developed countries, including the United States, and the increase will likely continue for some decades, the trend is a result of a cohort effect related to infection with hepatitis B and C viruses.
The LancetGlobal, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition
2,012 Citations2015Christopher J L Murray, Ryan M Barber +608 more
The Lancet Global HealthDisability weights for the Global Burden of Disease 2013 study
1,236 Citations2015Joshua A. Salomon, Juanita A. Haagsma +10 more
This study substantially expands the empirical basis for assessment of non-fatal outcomes in the GBD study and substantiates the notion that disability weights are sensitive to particular details in descriptions of health states, but robust to duration of outcomes.
The LancetA two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II
1,156 Citations2013Fiona E. Matthews, Antony Arthur +5 more
This study provides further evidence that a cohort effect exists in dementia prevalence, and later-born populations have a lower risk of prevalent dementia than those born earlier in the past century.
The LancetGBD 2010: design, definitions, and metrics
1,082 Citations2012Christopher J L Murray, Majid Ezzati +10 more
The LancetHealthy life expectancy for 187 countries, 1990–2010: a systematic analysis for the Global Burden Disease Study 2010
1,081 Citations2012Joshua A. Salomon, Haidong Wang +5 more
As life expectancy has increased, the number of healthy years lost to disability has also increased in most countries, consistent with the expansion of morbidity hypothesis, which has implications for health planning and health-care expenditure.
JAMADietary Intake of Antioxidants and Risk of Alzheimer Disease
1,060 Citations2002Marianne J. Engelhart
High dietary intake of vitamin C and vitamin E may lower the risk of Alzheimer disease.
The LancetAge-specific and sex-specific mortality in 187 countries, 1970–2010: a systematic analysis for the Global Burden of Disease Study 2010
805 Citations2012Haidong Wang, Laura Dwyer‐Lindgren +7 more
This work estimated life tables and annual numbers of deaths for 187 countries from 1970 to 2010 and developed a model to extrapolate mortality to 110 years of age, finding substantial heterogeneity exists across age groups, among countries, and over different decades.
ArXiv.orgDiscussion of "Analysis of variance--why it is more important than ever" by A. Gelman
655 Citations2005Tjur, Tue
A hierarchical analysis is proposed that automatically gives the correct ANOVA comparisons even in complex scenarios, and a new graphical display showing inferences about the standard deviations of each batch of effects is introduced.
The LancetAddressing liver disease in the UK: a blueprint for attaining excellence in health care and reducing premature mortality from lifestyle issues of excess consumption of alcohol, obesity, and viral hepatitis
591 Citations2014Roger Williams, Richard Aspinall +23 more
The aim of this Commission is to provide the strongest evidence base through involvement of experts from a wide cross-section of disciplines, making firm recommendations to reduce the unacceptable premature mortality and disease burden from avoidable causes and to improve the standard of care for patients with liver disease in hospital.
Population Health MetricsModeling causes of death: an integrated approach using CODEm
567 Citations2012Kyle J Foreman, Rafael Lozano +2 more
The utility of CODEm for the estimation of several major causes of death is demonstrated and it is shown that it produces better estimates of cause of death trends than previous methods and is less susceptible to bias in model specification.
The LancetUK health performance: findings of the Global Burden of Disease Study 2010
557 Citations2013Christopher J L Murray, Michael A. Richards +40 more
The American Journal of MedicineFruit and Vegetable Juices and Alzheimer’s Disease: The Kame Project
519 Citations2006Qi Dai, Amy R. Borenstein +3 more
Fruit and vegetable juices may play an important role in delaying the onset of Alzheimer's disease, particularly among those who are at high risk for the disease.
The LancetIncrease in primary liver cancer in the UK, 1979–94
505 Citations1997Simon D. Taylor‐Robinson, Graham R. Foster +3 more
1 McCarthy M. Bio-engineered tissues move towards the clinic, FDA expedites review of synthetic skins, and a composite skin substitute for surgical wounds.
Alzheimer s & DementiaTrends in the incidence and prevalence of Alzheimer's disease, dementia, and cognitive impairment in the United States
491 Citations2011Walter A. Rocca, Ronald C. Petersen +9 more
Although some decline was observed in the Minnesota cohort, no statistically significant trends were apparent in the community studies, and a significant reduction in cognitive impairment measured by neuropsychological testing was identified in the national survey.
Population Health MetricsAlgorithms for enhancing public health utility of national causes-of-death data
450 Citations2010Mohsen Naghavi, Susanna Makela +4 more
By mapping CoD through different ICD versions and redistributing GCs, it is believed the public health utility of coD data can be substantially enhanced, leading to an increased demand for higher quality CoD data from health sector decision-makers.
The LancetLiver cirrhosis mortality rates in Britain from 1950 to 2002: an analysis of routine data
443 Citations2006David A. Leon, Jim McCambridge
Current alcohol policies in Britain should be assessed by the extent to which they can successfully halt the adverse trends in liver cirrhosis mortality, including the situation in Scotland, which is now one of the highest in western Europe.
Journal of Human HypertensionSalt reduction in the United Kingdom: a successful experiment in public health
441 Citations2013Feng J. He, Hannah Brinsden +1 more
A step-by-step guide of developing and implementing a national salt reduction strategy, which other countries could follow, is provided, which will result in major public health improvements and cost savings.
International Journal of EpidemiologyPreventing the onset of major depressive disorder: A meta-analytic review of psychological interventions
417 Citations2014Kim van Zoonen, Claudia Buntrock +5 more
Prevention of depression seems feasible and may, in addition to treatment, be an effective way to delay or prevent the onset of depressive disorders.
Annals of the Rheumatic DiseasesReflecting on the global burden of musculoskeletal conditions: lessons learnt from the Global Burden of Disease 2010 Study and the next steps forward
257 Citations2014Damian G Hoy, Emma Smith +8 more
An overview of the strengths, limitations and lessons learned from estimating the burden from musculoskeletal conditions in the Global Burden of Disease 2010 Study (GBD 2010 Study) is provided.
British Journal of DermatologyPsoriasis in the community: prevalence, severity and patients' beliefs and attitudes towards the disease
251 Citations1996G.J. NEVITT, P.E. Hutchinson
The findings, particularly in relation to patients' attitude to the disease, disease severity, fluctuation in severity and referral requirements, are of potential interest in health care planning.
International PsychogeriatricsSystematic review of health behavioral risks and cognitive health in older adults
241 Citations2009Yunhwan Lee, Joung Hwan Back +6 more
Accumulating evidence supporting health behavioral effects in reducing the risk of cognitive decline and dementia is demonstrated, indicating potential benefits of healthy lifestyles in protecting cognitive health in later life.
BMJDesigning prevention programmes to reduce incidence of dementia: prospective cohort study of modifiable risk factors
236 Citations2010Karen Ritchie, Isabelle Carrière +4 more
Increasing crystallised intelligence and fruit and vegetable consumption and eliminating depression and diabetes are likely to have the biggest impact on reducing the incidence of dementia, outweighing even the effect of removing the principal known genetic risk factor.
BMJDetection of depression and anxiety in primary care: follow up study
205 Citations2002David Kessler, Olive Bennewith +2 more
Whether depression or anxiety not diagnosed during one general practice consultation is diagnosed during follow up or is self limiting and of no clinical importance is determined.
Population Health MetricsAssessing disability weights based on the responses of 30,660 people from four European countries
202 Citations2015Juanita A. Haagsma, Charline Maertens de Noordhout +8 more
Assessment of the feasibility of rescaling based on a discrete choice formulation of the PHE question indicated that this approach may not be suitable for use in a web-based survey of the general population, as well as an alternative approach using non-parametric regression.
Annual Review of Public HealthCan Dementia Be Prevented? Brain Aging in a Population-Based Context
188 Citations2004Mary N. Haan, Robert B. Wallace
Understanding the reasons for differences between populations in genetic vulnerability and environmental exposures may help to identify modifiable risk factors that may lead to effective prevention of vascular and Alzheimer's dementia.
Journal of HepatologyIncidence and prevalence of cirrhosis in the United Kingdom, 1992–2001: A general population-based study
178 Citations2008Kate M. Fleming, Guruprasad P. Aithal +3 more
There was a 45% rise in the incidence of cirrhosis during the decade 1992-2001 in the UK and a 68% increase in prevalence.
PLoS MedicineAnalysing Recent Socioeconomic Trends in Coronary Heart Disease Mortality in England, 2000–2007: A Population Modelling Study
156 Citations2012Madhavi Bajekal, Shaun Scholes +5 more
A modeling study estimates the extent to which specific risk factors and changes in uptake of treatment contributed to the declines in coronary heart disease mortality in England between 2000 and 2007, across and within socioeconomic groups.
The LancetThe future of life expectancy and life expectancy inequalities in England and Wales: Bayesian spatiotemporal forecasting
141 Citations2015James E. Bennett, Guangquan Li +6 more
Demographic ResearchAn integrated approach to cause-of-death analysis: cause-deleted life tables and decompositions of life expectancy
141 Citations2008Hiram Beltrán‐Sánchez, Samuel H. Preston +1 more
The paradox that cancer is responsible for more years of life lost in 2000 than in 1970 despite the fact that declines in cancer mortality contributed to advances in life expectancy between 1970 and 2000 is demonstrated.
PLoS MedicineWhat Can We Conclude from Death Registration? Improved Methods for Evaluating Completeness
126 Citations2010Christopher J L Murray, Julie Knoll Rajaratnam +3 more
A suite of demographic methods that estimate the fraction of deaths registered and counted by civil registration systems are evaluated, and three variants are identified that generally perform the best.
Population Health MetricsImproving the public health utility of global cardiovascular mortality data: the rise of ischemic heart disease
117 Citations2011Ryan M Ahern, Rafael Lozano +4 more
Age-adjusted death rate increases for ischemic heart disease in low- and middle-income countries, such as Argentina and South Africa, highlight the rise of the cardiovascular epidemic in regions where public health efforts have historically focused on infectious diseases.
PLoS ONERates of Decline in Alzheimer Disease Decrease with Age
102 Citations2012Dominic Holland, Rahul S. Desikan +3 more
The results imply that the phenotypic expression of AD is relatively mild in individuals older than approximately 85 years, and this may affect the ability to distinguish AD from normal aging in the very old.
Journal of Public HealthRemoving the health domain from the Index of Multiple Deprivation 2004—effect on measured inequalities in census measure of health
84 Citations2006Jean Adams, Martin White
There was excellent agreement between the deprivation quintiles that small areas were assigned to by IMD 2004 and IMD2004-minus-health and there was little, practical, effect on measured socioeconomic inequalities in census measures of health.
The American Journal of GastroenterologyDiagnosis of Liver Cirrhosis in England, a Cohort Study, 1998–2009: A Comparison With Cancer
75 Citations2014Sonia Ratib, Joe West +2 more
The occurrence of cirrhosis increased more than that of the top four cancers during 1998 to 2009 in England in England, and the percentage change in incidence for both men and women and all etiology types was greater than that seen for the topFour most commonly diagnosed cancers.
Journal of Alzheimer s DiseaseDementia (Including Alzheimer's Disease) can be Prevented: Statement Supported by International Experts
73 Citations2013A. David Smith, Kristine Yaffe
This work proposes that a concerted effort be made to discover modifiable risk factors for dementia and to exploit those already identified, and recommends that middle-aged people be encouraged to stop smoking; exercise; eat diets rich in fruit and vegetables and fish; avoid becoming obese and diabetic; and treat high blood pressure.
The Primary Care Companion to The Journal of Clinical PsychiatryManagement of Generalized Anxiety Disorder in Primary Care
53 Citations2010Jonathan Davidson, Douglas E. Feltner +1 more
While the development of novel treatments evolves, current management approaches can focus on improving identification and defining optimal use of available therapies for GAD.
HeartIs the prevalence of coronary heart disease falling in British men?
48 Citations2001Fiona Lampe, R W Morris +4 more
It is suggested that middle aged British men are less likely to experience symptoms of angina than in previous decades but are just as likely to have a history of diagnosed CHD.
BMJDevolution and divergence in UK health policies
37 Citations2008Scott L. Greer
Scott Greer explores how political variation in the UK has led to differences between the health systems of its four nations since devolution.
Population and Development ReviewTrends in Causes of Death in Low‐Mortality Countries: Implications for Mortality Projections
37 Citations2014John Bongaarts
Overall trends in mortality by cause since the middle of the twentieth century is summarized and the implications for projections are discussed, finding that mortality projections can be improved by taking into account the distorting effects of smoking.
British Journal of General PracticeImproving the detection and management of anxiety disorders in primary care
30 Citations2011Marta Buszewicz, Carolyn Chew‐Graham
There has been considerable emphasis on encouraging GPs to improve their skills in the diagnosis and management of depression, yet anxiety disorders have been relatively neglected and GP rates of diagnosis and treatment of anxiety disorders are much lower than expected.
The LancetUK Biobank comes of age
24 Citations2015Simon G. Thompson, Peter Willeit
The paper’s conclusion that self-reported information generally provides stronger predictors of mortality than biological measurements might not withstand the test of time is concluded.
Researchfor enhancing public health utility of national causes-of-death data
21 Citations2010Mohsen Naghavi, Susanna Makela +4 more
By mapping CoD through different ICD versions and redistributing GCs, it is believed the public health utility of coD data can be substantially enhanced, leading to an increased demand for higher quality CoD data from health sector decision-makers.
PubMed[Inequalities in health expectancies in England and Wales--small area analysis from the 2001 Ccensus.
17 Citations2007Domenica Rasulo, Madhavi Bajekal +1 more
Inequalities were examined both nationally and within regions by computing life expectancies and health expectancies in groups of wards aggregated according to the Carstairs deprivation score, showing that the inequality gaps were significantly larger for health Expectancies compared with life expectancy; they were wider for disability-free life expectancy than healthy life expectancy%; and, for all measures, were widest for males.
The LancetMetrics for what?
14 Citations2013Richard Horton
The geometry of the tangent bundle equipped with a two-parameter family of metrics is studied, deforming the Sasaki and Cheeger-Gromoll metrics and it is shown that one can always find parameters ensuring positive scalar curvature.
Journal of Public HealthPublic health research in the UK: a report with a European perspective
8 Citations2013Mark I. McCarthy, M Dyakova +1 more
With growing expertise and capacity across other EU countries, the UK should take more active leadership in European collaboration and strategic coordination between public health researchers and practitioners would strengthen research for policy and practice.
Health & PlaceA neighbourhood level mortality classification of England and Wales, 2006–2009
8 Citations2014Mark Green, Daniel Vickers +1 more
An overview of a neighbourhood level classification of mortality for England and Wales (2006-2009) is provided to help inform policy development, resource allocation and targeting of services.
European Journal of Public HealthTracking uptake of innovations from the European Union Public Health Programme
6 Citations2013Margaretha Voss, Kristina Alexanderson +1 more
The uptake of public health innovation projects at country level was addressed in PHIRE, a collaboration of the European Public Health Association and seven partners, to enable cross-national innovation and transfer in fields of health information, health threats and health promotion.
Sexually Transmitted DiseasesPublic Health and Prevention
4 Citations2013Elissa Meites, Kimberly Workowski
Clinically, the prevention and control of STDs are based on five major strategies: education and counseling, screening, diagnosis and treatment, partner services, and vaccination, which can be applied to major public health problems in STD control and prevention.
White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)Death in England and Wales: Using a classificatory approach for researching mortality
3 Citations2013Mark Green