Top Research Papers on Organic Chemistry

The second edition of The Chemistry of Clay-Organic Reactions book provides a comprehensive and fully updated summary of the literature on the interactions of clay minerals with organic molecules, including reaction mechanisms and bonding modes together with their practical and industrial applications. The reader will gain an insight into the formation and properties of complexes between clay minerals and a variety of organic compounds and the use of such complexes as sorbents and carriers of organic pollutants, pesticides, dyes, and pharmaceuticals. KEY FEATURES An authoritative resource prov...

Abstract Porous organic molecular materials are a subclass of porous solids that are defined by their modular, molecular structures, and the absence of extended covalent or coordination bonding in the solid‐state. As a result, porous molecular materials are soluble and they can be processed into different forms, such as mixed matrix membranes. The structure of the porous modules can be fine‐tuned for specific applications, such as gas isotope separations, and in some cases the solid‐state properties of these materials can be defined by the structure of the porous molecule as viewed in isolatio...

Current global crises related to clean energy and the environment entail the development of materials that are capable of addressing these challenges. Metal-organic frameworks (MOFs), a class of functional materials assembled from metal-containing nodes and organic ligands via coordination bonds, have been successfully developed for various applications, including catalysis, toxic chemical removal, and gas storage and separation, as a result of their highly tailorable nature and precisely engineered pore structures. In particular, the exceptionally high surface areas and porosities of MOFs are...

Combined efforts from molecular biology, systems biology, organic chemistry and chemical engineering will establish a whole new toolbox for chemistry.

Abstract The pores in metal–organic frameworks (MOFs) can be functionalized by placing chemical entities along the backbone and within the backbone. This chemistry is enabled by the architectural, thermal, and chemical robustness of the frameworks and the ability to characterize them by many diffraction and spectroscopic techniques. The pore chemistry of MOFs is articulated in terms of site isolation, coupling, and cooperation and relate that to their functions in guest recognition, catalysis, ion and electron transport, energy transfer, pore‐dynamic modulation, and interface construction. It ...

A series of new POCs with dimeric cages with odd-even behaviors, unprecedented trimeric triangular prisms, and the largest recorded hexameric octahedra have been prepared, shedding light on the rational design of POC materials for practical applications.

This work investigated whether enantioselectivity data from a reaction can be quantitatively connected to the attributes of reaction components, such as catalyst and substrate structural features, to harness data for asymmetric catalyst design and developed a workflow to relate computationally derived features of Reaction components to enantiOSElectivity using data science tools.

A synopsis of the history of data-driven modeling in organic chemistry and the terms used to describe these endeavors is provided and a timeline of the steps that led to its current state is included.

Selenium, originally described as a toxin, turns out to be a crucial trace element for life that appears as selenocysteine and its dimer, selenocystine. From the point of view of drug developments, selenium-containing drugs are isosteres of sulfur and oxygen with the advantage that the presence of the selenium atom confers antioxidant properties and high lipophilicity, which would increase cell membrane permeation leading to better oral bioavailability. In this article, we have focused on the relevant features of the selenium atom, above all, the corresponding synthetic approaches to access a ...

Abstract Proton storage in rechargeable aqueous zinc‐ion batteries (ZIBs) is attracting extensive attention owing to the fast kinetics of H + insertion/extraction. However, it has not been achieved in organic materials‐based ZIBs with a mild electrolyte. Now, aqueous ZIBs based on diquinoxalino [2,3‐ a :2′,3′‐ c ] phenazine (HATN) in a mild electrolyte are developed. Electrochemical and structural analysis confirm for the first time that such Zn–HATN batteries experience a H + uptake/removal behavior with highly reversible structural evolution of HATN. The H + uptake/removal endows the Zn–HATN...

Electrochemical and structural analysis confirm for the first time that such Zn/HATN batteries experience a H + uptake/removal behavior with highly reversible structural evolution of HATN.

Summary The study of hydrogen-bonding (H-bonding) interactions can be traced back to over a century ago. Recent practices on H-bonding chemistry for constructing extended frameworks have led to the emergence of hydrogen-bonded organic frameworks (HOFs). Rational combinations of molecular skeletons and hydrogen-bonded units result in HOFs with porosity or flexibility. HOF structures might be predicted through framework topology and tuned by adjusting linker lengths for getting isostructural HOFs, although there are some HOFs showing responsive flexibility for specific molecular recognitions. Be...

Covalent organic frameworks (COF) are a class of crystalline porous polymer that enables the covalent integration of organic units into periodically ordered skeletons and aligned polygonal pores. This structural feature sets a new polymer platform that enables the design of not only structures but also functions. Especially, primary- and high-order structures of COFs are fully pre-designable and synthetically controllable, offering a new diagram of chemistry in designing functional materials. Progress in chemistry and materials science over the past 15 years has greatly enhanced our capability...

Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious "black box" needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By "lifting the veil" on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.

This review summarized recently developed organic luminescent and photoacoustic materials, ranging from small molecules to conjugated polymers, and elucidated the challenges and prospective of these NIR-II organic dyes for potential clinical applications.

This review explores the properties that led to such widespread use of chlorinated solvents, why there is now an increasing drive to minimize usage, and what alternatives are currently available.

Covalent organic frameworks emerged as a class of polymers that enable the construction of ordered skeletons and pores via simple polymerization, offering a unique chemistry platform that greatly enhances our capability of designing organic structures and functions. In this perspective, we analyze the structural design and synthesis by highlighting distinct features and bottleneck problems. We scrutinize major functions by correlating structure-function relationships and disclosing the key structural parameters and interfaces that control various interplays to show the key achievements and our...

This review will offer a holistic summary of the chemistry, uniqueness, synthesis, and applications of Hf/Ce(iv)-MOFs with a focus on presenting the development in the Hf/, Ce(iv) based MOF clusters, topologies, ligand structures, synthetic strategies, and practical applications.

Paired electrolysis is highly valuable from the viewpoint of efficiency as well as atom and energy economies. In order to optimize the latter two for chemical reactions, the development of paired electrochemical processes is necessary. When both of the electrodes in an electrochemical cell (divided and undivided) are applied as working electrodes, and both sides of the processes (oxidation and reduction) yield valuable compounds, this ideal electrolysis phenomena is defined as paired electrosynthesis. This paired electrolysis offers the opportunity to reduce the spent energy and time, when com...

Precise control of the pore size and environment of metal–organic framework (MOF) is a necessary condition for achieving high performance of gas adsorption and separation. After nearly two decades of development, the synthesis of MOF materials has gradually evolved from exploration and trial to precise-design, including function-oriented microstructure design and optimization, pore size tailoring, and secondary building unit (SBU) modification. The unique pore environments of MOF materials enable their advantages in gas adsorption and separation applications. In addition, the introduction of i...