Top Research Papers on Organic Chemistry

The second edition of The Chemistry of Clay-Organic Reactions book provides a comprehensive and fully updated summary of the literature on the interactions of clay minerals with organic molecules, including reaction mechanisms and bonding modes together with their practical and industrial applications. The reader will gain an insight into the formation and properties of complexes between clay minerals and a variety of organic compounds and the use of such complexes as sorbents and carriers of organic pollutants, pesticides, dyes, and pharmaceuticals. KEY FEATURES An authoritative resource prov...

Abstract Porous organic molecular materials are a subclass of porous solids that are defined by their modular, molecular structures, and the absence of extended covalent or coordination bonding in the solid‐state. As a result, porous molecular materials are soluble and they can be processed into different forms, such as mixed matrix membranes. The structure of the porous modules can be fine‐tuned for specific applications, such as gas isotope separations, and in some cases the solid‐state properties of these materials can be defined by the structure of the porous molecule as viewed in isolatio...

Current global crises related to clean energy and the environment entail the development of materials that are capable of addressing these challenges. Metal-organic frameworks (MOFs), a class of functional materials assembled from metal-containing nodes and organic ligands via coordination bonds, have been successfully developed for various applications, including catalysis, toxic chemical removal, and gas storage and separation, as a result of their highly tailorable nature and precisely engineered pore structures. In particular, the exceptionally high surface areas and porosities of MOFs are...

Combined efforts from molecular biology, systems biology, organic chemistry and chemical engineering will establish a whole new toolbox for chemistry.

Abstract The pores in metal–organic frameworks (MOFs) can be functionalized by placing chemical entities along the backbone and within the backbone. This chemistry is enabled by the architectural, thermal, and chemical robustness of the frameworks and the ability to characterize them by many diffraction and spectroscopic techniques. The pore chemistry of MOFs is articulated in terms of site isolation, coupling, and cooperation and relate that to their functions in guest recognition, catalysis, ion and electron transport, energy transfer, pore‐dynamic modulation, and interface construction. It ...

A series of new POCs with dimeric cages with odd-even behaviors, unprecedented trimeric triangular prisms, and the largest recorded hexameric octahedra have been prepared, shedding light on the rational design of POC materials for practical applications.

This work investigated whether enantioselectivity data from a reaction can be quantitatively connected to the attributes of reaction components, such as catalyst and substrate structural features, to harness data for asymmetric catalyst design and developed a workflow to relate computationally derived features of Reaction components to enantiOSElectivity using data science tools.

A synopsis of the history of data-driven modeling in organic chemistry and the terms used to describe these endeavors is provided and a timeline of the steps that led to its current state is included.

Selenium, originally described as a toxin, turns out to be a crucial trace element for life that appears as selenocysteine and its dimer, selenocystine. From the point of view of drug developments, selenium-containing drugs are isosteres of sulfur and oxygen with the advantage that the presence of the selenium atom confers antioxidant properties and high lipophilicity, which would increase cell membrane permeation leading to better oral bioavailability. In this article, we have focused on the relevant features of the selenium atom, above all, the corresponding synthetic approaches to access a ...

Abstract Proton storage in rechargeable aqueous zinc‐ion batteries (ZIBs) is attracting extensive attention owing to the fast kinetics of H + insertion/extraction. However, it has not been achieved in organic materials‐based ZIBs with a mild electrolyte. Now, aqueous ZIBs based on diquinoxalino [2,3‐ a :2′,3′‐ c ] phenazine (HATN) in a mild electrolyte are developed. Electrochemical and structural analysis confirm for the first time that such Zn–HATN batteries experience a H + uptake/removal behavior with highly reversible structural evolution of HATN. The H + uptake/removal endows the Zn–HATN...

Electrochemical and structural analysis confirm for the first time that such Zn/HATN batteries experience a H + uptake/removal behavior with highly reversible structural evolution of HATN.

Summary The study of hydrogen-bonding (H-bonding) interactions can be traced back to over a century ago. Recent practices on H-bonding chemistry for constructing extended frameworks have led to the emergence of hydrogen-bonded organic frameworks (HOFs). Rational combinations of molecular skeletons and hydrogen-bonded units result in HOFs with porosity or flexibility. HOF structures might be predicted through framework topology and tuned by adjusting linker lengths for getting isostructural HOFs, although there are some HOFs showing responsive flexibility for specific molecular recognitions. Be...

Covalent organic frameworks (COF) are a class of crystalline porous polymer that enables the covalent integration of organic units into periodically ordered skeletons and aligned polygonal pores. This structural feature sets a new polymer platform that enables the design of not only structures but also functions. Especially, primary- and high-order structures of COFs are fully pre-designable and synthetically controllable, offering a new diagram of chemistry in designing functional materials. Progress in chemistry and materials science over the past 15 years has greatly enhanced our capability...

Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious "black box" needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By "lifting the veil" on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.

This review summarized recently developed organic luminescent and photoacoustic materials, ranging from small molecules to conjugated polymers, and elucidated the challenges and prospective of these NIR-II organic dyes for potential clinical applications.

This review explores the properties that led to such widespread use of chlorinated solvents, why there is now an increasing drive to minimize usage, and what alternatives are currently available.

Covalent organic frameworks emerged as a class of polymers that enable the construction of ordered skeletons and pores via simple polymerization, offering a unique chemistry platform that greatly enhances our capability of designing organic structures and functions. In this perspective, we analyze the structural design and synthesis by highlighting distinct features and bottleneck problems. We scrutinize major functions by correlating structure-function relationships and disclosing the key structural parameters and interfaces that control various interplays to show the key achievements and our...

This review will offer a holistic summary of the chemistry, uniqueness, synthesis, and applications of Hf/Ce(iv)-MOFs with a focus on presenting the development in the Hf/, Ce(iv) based MOF clusters, topologies, ligand structures, synthetic strategies, and practical applications.

Paired electrolysis is highly valuable from the viewpoint of efficiency as well as atom and energy economies. In order to optimize the latter two for chemical reactions, the development of paired electrochemical processes is necessary. When both of the electrodes in an electrochemical cell (divided and undivided) are applied as working electrodes, and both sides of the processes (oxidation and reduction) yield valuable compounds, this ideal electrolysis phenomena is defined as paired electrosynthesis. This paired electrolysis offers the opportunity to reduce the spent energy and time, when com...

Precise control of the pore size and environment of metal–organic framework (MOF) is a necessary condition for achieving high performance of gas adsorption and separation. After nearly two decades of development, the synthesis of MOF materials has gradually evolved from exploration and trial to precise-design, including function-oriented microstructure design and optimization, pore size tailoring, and secondary building unit (SBU) modification. The unique pore environments of MOF materials enable their advantages in gas adsorption and separation applications. In addition, the introduction of i...

This work demonstrates that Transformer Neural Networks learn atom-mapping information between products and reactants without supervision or human labeling, and provides the missing link between data-driven and rule-based approaches for numerous chemical reaction tasks.

The role of ROC in atmospheric chemistry and the challenges inherent in measuring and modeling ROC are characterized, and recent progress toward achieving mass closure is highlighted.

This review discusses MOFs as structures; emphasizes their synthesis strategies, properties, and applications; explores the existing methods of using immobilization processes of various enzymes; and lists their possible chemical modifications and combinations with other compounds to formulate the ideal supports for a given application.

The current text provides a comprehensive introduction to essential oils, their biosynthesis, naming, analysis, and chemistry. Importantly, this text quickly brings the reader up to a level of competence in the authentication of essential oils and their components. It gives detailed descriptions of enantiomers and other forms of stereoisomers relevant to the study of natural volatiles and essential oils. The text also describes GC-MS work and provides tips on rapid calculation of arithmetic indices, how to interpret suggested names from the NIST mass spectral library, and what additional effor...

Catalytic polymerization pathways in advanced oxidation processes (AOPs) have recently drawn much attention for organic pollutant elimination owing to the rapid removal kinetics, high selectivity, and recovery of organic carbon from wastewater. This work presents a review on the polymerization regimes in AOPs and their applications in wastewater decontamination. The review mainly highlights three critical issues in polymerization reactions induced by persulfate activation (Poly-PS-AOPs), including heterogeneous catalysts, persulfate activation pathways, and properties of organic substrates. Th...

The aim of this work is to put the recent progress into a historical context and provide avenues toward a more comprehensive understanding of solvents in multicomponent supramolecular systems.

This tutorial review introduces different types of POPs and their classification and functions for Li-chemistry-based batteries. In situ characterization studies are also discussed to highlight their importance and applicability for POPs.

The results demonstrate the feasibility and versatility of metal-organic frameworks as energy storage materials for a wide range of battery chemistries.

Strong reducing agents ( 2 are commonly employed for these reactions; however, considerations including expense, ease of use, safety, and waste generation limit the practicality of these methods. Recent approaches utilizing energy from multiple photons or electron-primed photoredox catalysis have accessed reduction potentials equivalent to Li 0 and shown how this enables selective transformations of aryl chlorides via aryl radicals. However, in some cases, low stability of catalytic intermediates can limit turnover numbers. Herein, we report the ability of CdS nanocrystal quantum dots (QDs) to...

Open AccessCCS ChemistryRESEARCH ARTICLE1 Jul 2021Copper (I)–Organic Frameworks for Catalysis: Networking Metal Clusters with Dynamic Covalent Chemistry Rong-Jia Wei†, Hou-Gan Zhou†, Zhi-Yin Zhang, Guo-Hong Ning and Dan Li Rong-Jia Wei† College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou 510632 , Hou-Gan Zhou† College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan Univer...

Abstract Precise oligomeric materials constitute a growing area of research with implications for various applications as well as fundamental studies. Notably, this field of science which can be termed macro‐organic chemistry, draws inspiration from both traditional polymer chemistry and organic synthesis, combining the molecular precision of organic chemistry with the materials properties of macromolecules. Discrete oligomers enable access to unprecedented materials properties, for example, in self‐assembled structures, crystallization, or optical properties. The degree of control over oligom...

Tetracyclines (TCs) are a large family of broad-spectrum antibiotics with one of the highest aquatic persistence after release from humans and animals. Hence, TCs are known to generate antibiotic resistance along with estrogenic and other toxic effects in non-target organisms. Unfortunately, the detection and removal of TCs from aqueous matrices remain challenging. For this purpose, we review metal–organic frameworks (MOFs), which have emerged as effective alternatives, given their photocatalytic and adsorptive capabilities. MOFs exhibit large interactive surface area and tunable structure and...

This review will focus on A-D-A molecules used in OPVs from the viewpoint of chemists, highlighting the chemical structure-property relationships and the underlying reasons for their outstanding performance.

Five synthetic strategies for COF synthesis are rationalized, namely: modulation, mixed linker/linkage, sub-stoichiometric reaction, framework isomerism, and linker exchange, which highlight the dynamic covalent chemistry to regulate the growth and to modify the properties of COFs.

A strategy to synthesize COFs with azo linkages based on an in situ linker exchange strategy which transforms imine-linked COFs into their azo-linked counterparts, and explore the unique properties of azos- linked COFs.

The design of composite phase change materials (PCMs) for thermal energy storage has attracted increasing attention owing to their high latent heat storage capability, enhanced thermal transfer performance, and low volume variation in addition to being seepage free. This review aims to provide techniques for engineering the thermal parameters of composite PCMs (e.g., latent heat, thermal conductivity, durability, and thermal stability) for several advanced large-scale applications and for producing desired thermophysical, chemical, and mechanical properties. In addition, approaches and materia...

Three specific approaches developed by the group to facilitate the design and assembly of finely tuned MOFs are detailed, based on careful geometrical consideration and a deep study and understanding of the existing nets and topologies.

Abstract To date, about two dozen low-mass embedded protostars exhibit rich spectra with lines of complex organic molecules (COMs). These protostars seem to possess a different enrichment in COMs. However, the statistics of COM abundance in low-mass protostars are limited by the scarcity of observations. This study introduces the Perseus ALMA Chemistry Survey (PEACHES), which aims at unbiasedly characterizing the chemistry of COMs toward the embedded (Class 0/I) protostars in the Perseus molecular cloud. Of the 50 embedded protostars surveyed, 58% of them have emission from COMs. 56%, 32%, and...

A review presenting water as the logical reaction medium for the future of organic chemistry and how water is playing unique roles in each, specifically with regard to its use in organic synthesis.

The BioAge R package, a toolkit to facilitate measurement of biological age for geroscience, applies to safety lab data from the CALERIE™ randomized controlled trial, the first-ever human trial of long-term calorie restriction in healthy, non-obese adults, to test effects of intervention on biological aging.