Ethical, and practical issues in applying functional imaging to the clinical management of Alzheimer’s disease
Brain and CognitionPublished 1 December 2002
Allyson Rosen, Arun L.W. Bokde, Allison Pearl, Jerome A. Yesavage
Citations24
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SJR score0.74
SNIP0.79
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TL;DR
This review outlines ethical, legal, and practical issues related to conducting functional imaging research with Alzheimer's disease patients and various potential clinical applications of functional imaging.
Abstract
This review outlines ethical, legal, and practical issues related to conducting functional imaging research with Alzheimer's disease (AD) patients. Imaging techniques, with an emphasis on functional MRI and positron emission tomography, are compared and contrasted with respect to the manner in which they can be applied to issues of clinical relevance to AD. Methodological difficulties are raised to assist with critical evaluation of current imaging results. Various potential clinical applications of functional imaging are briefly reviewed and discussed with respect to associated ethical conflicts.
Keywords
MedicineArts and Humanities
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Medical Entomology and ZoologyPrinciples of neural aging
54 Citations1997Sérgio U. Dani, Akira Hori +1 more
Theories of aging, secular changes and aging: how old is the authors' brain?
Journal of Geriatric Psychiatry and NeurologyReview of Outcome Measurement Instruments in Alzheimer's Disease Drug Trials: Psychometric Properties of Functional and Quality of Life Scales
53 Citations2000Louise Demers, Mark Oremus +3 more
The psychometric properties of functional and quality of life outcome measures that were used for the purpose of showing changes in antidementia drug trials for Alzheimer's disease are described and critiqued.
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