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An fMRI Study of the Effects of Psychostimulants on Default-Mode Processing During Stroop Task Performance in Youths With ADHD

American Journal of PsychiatryPublished 16 September 2009
Bradley S. Peterson, Marc N. Potenza, Zhishun Wang, Hongtu Zhu, Andrés Martín, Rachel Marsh
Citations258
SJR quartileQ1
SJR score5.27
SNIP3.68

TL;DR

Stimulants seem to improve symptoms in youths with ADHD by normalizing activity within this circuit and improving its functional interactions with the lateral prefrontal cortex, components of a circuit in which activity has been shown to correlate with the degree of mind-wandering during attentional tasks.

Abstract

Psychostimulants in youths with ADHD improved suppression of default-mode activity in the ventral anterior cingulate and posterior cingulate cortices, components of a circuit in which activity has been shown to correlate with the degree of mind-wandering during attentional tasks. Stimulants seem to improve symptoms in youths with ADHD by normalizing activity within this circuit and improving its functional interactions with the lateral prefrontal cortex.

Keywords

MedicineNeuroscience