Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes
NaturePublished 1 October 1984
Rolf Müller, Erwin F. Wagner
Citations301
SJR quartileQ1
SJR score18.29
SNIP10.16
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TL;DR
Transfer of mouse or human c-fos proto-oncogenes into F9 teratocarcinoma stem cells results in expression of c-Fos mRNA and protein, suggesting that c- fos plays a role in cellular differentiation.
Abstract
Transfer of mouse or human c-fos proto-oncogenes into F9 teratocarcinoma stem cells results in expression of c-fos mRNA and protein. This is accompanied by the appearance of morphologically altered cells which express several specific markers characteristic of differentiated cells, suggesting that c-fos plays a role in cellular differentiation.
Keywords
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